PS 48

CAS# 1180676-32-7

PS 48

2D Structure

Catalog No. BCC7859----Order now to get a substantial discount!

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PS 48: 5mg $69 In Stock
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3D structure

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PS 48

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Chemical Properties of PS 48

Cas No. 1180676-32-7 SDF Download SDF
PubChem ID 44141940 Appearance Powder
Formula C17H15ClO2 M.Wt 286.75
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in DMSO > 10 mM
Chemical Name (Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
SMILES C1=CC=C(C=C1)C(=CC(=O)O)CCC2=CC=C(C=C2)Cl
Standard InChIKey LLJYFDRQFPQGNY-QINSGFPZSA-N
Standard InChI InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of PS 48

DescriptionPhosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site.

PS 48 Dilution Calculator

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PS 48 Molarity Calculator

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Preparing Stock Solutions of PS 48

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4874 mL 17.4368 mL 34.8736 mL 69.7472 mL 87.184 mL
5 mM 0.6975 mL 3.4874 mL 6.9747 mL 13.9494 mL 17.4368 mL
10 mM 0.3487 mL 1.7437 mL 3.4874 mL 6.9747 mL 8.7184 mL
50 mM 0.0697 mL 0.3487 mL 0.6975 mL 1.3949 mL 1.7437 mL
100 mM 0.0349 mL 0.1744 mL 0.3487 mL 0.6975 mL 0.8718 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on PS 48

High-tech breakthrough DNA scanner for reading sequence and detecting gene mutation. A powerful 1 lb, 20 micron resolution, 16-bit personal scanner (PS) that scans 17" x 14" X-ray film in 48 s, with laser, UV and white light sources.[Pubmed:8379664]

Appl Biochem Biotechnol. 1993 Jun;41(3):219-31.

The 17" x 14" X-ray film, gels, and blots are widely used in DNA research. However, DNA laser scanners are costly and unaffordable for the majority of surveyed biotech scientists who need it. The high-tech breakthrough analytical personal scanner (PS) presented in this report is an inexpensive 1 lb hand-held scanner priced at 2-4% of the bulky and costly 30-95 lb conventional laser scanners. This PS scanner is affordable from an operation budget and biotechnologists, who originate most science breakthroughs, can acquire it to enhance their speed, accuracy, and productivity. Compared to conventional laser scanners that are currently available only through hard-to-get capital-equipment budgets, the new PS scanner offers improved spatial resolution of 20 microns, higher speed (scan up to 17" x 14" molecular X-ray film in 48 s), 1-32,768 gray levels (16-bits), student routines, versatility, and, most important, affordability. Its programs image the film, read DNA sequences automatically, and detect gene mutation. In parallel to the wide laboratory use of PC computers instead of mainframes, this PS scanner might become an integral part of a PC-PS powerful and cost-effective system where the PS performs the digital imaging and the PC acts on the data.

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