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Interiotherin C

CAS# 460090-65-7

Interiotherin C

2D Structure

Catalog No. BCN3636----Order now to get a substantial discount!

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Quality Control of Interiotherin C

3D structure

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Interiotherin C

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Chemical Properties of Interiotherin C

Cas No. 460090-65-7 SDF Download SDF
PubChem ID 10099233 Appearance Powder
Formula C30H36O10 M.Wt 556.6
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC=C(C)C(=O)OC1C(C(C(C2=CC3=C(C(=C2C4=C(C(=C(C=C14)OC)OC)OC)OC)OCO3)OC(=O)C)C)C
Standard InChIKey HIGLJZHMTBHEQS-HWZXAUMYSA-N
Standard InChI InChI=1S/C30H36O10/c1-10-14(2)30(32)40-25-16(4)15(3)24(39-17(5)31)19-12-21-27(38-13-37-21)29(36-9)23(19)22-18(25)11-20(33-6)26(34-7)28(22)35-8/h10-12,15-16,24-25H,13H2,1-9H3/b14-10-/t15-,16+,24-,25-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Interiotherin C

The herbs of Schisandra rubriflora

Biological Activity of Interiotherin C

Description1. Interiotherin C may be valuable antitumor promoters or chemopreventors.

Interiotherin C Dilution Calculator

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Interiotherin C Molarity Calculator

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Preparing Stock Solutions of Interiotherin C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7966 mL 8.9831 mL 17.9662 mL 35.9324 mL 44.9156 mL
5 mM 0.3593 mL 1.7966 mL 3.5932 mL 7.1865 mL 8.9831 mL
10 mM 0.1797 mL 0.8983 mL 1.7966 mL 3.5932 mL 4.4916 mL
50 mM 0.0359 mL 0.1797 mL 0.3593 mL 0.7186 mL 0.8983 mL
100 mM 0.018 mL 0.0898 mL 0.1797 mL 0.3593 mL 0.4492 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Interiotherin C

Interiotherins C and D, two new lignans from Kadsura interior and antitumor-promoting effects of related neolignans on Epstein-Barr virus activation.[Pubmed:12350139]

J Nat Prod. 2002 Sep;65(9):1242-5.

Two new lignans, interiotherins C (1) and D (2), together with the known compounds interiorin (3), heteroclitin F (4), neokadsuranin (5), heteroclitin D (6), kadsurin (7), gomisin A (8), schisandrin C (9), interiotherin A (10), angeloylgomisin R (11), gomisin G (12), interiotherin B (13), and gomisin C (14), were isolated from the stems of Kadsura interior. The structures and stereochemistries of the new compounds were determined from mass, CD, and NMR spectral data. Fourteen neolignans were screened as potential antitumor promoters by examining their ability to inhibit Epstein-Barr virus early antigen (EBV-EA) activation (induced by 12-O-tetradecanoylphorbol-13-acetate) in Raji cells. Neokadsuranin (5) and schisandrin C (9) were the most potent compounds. These data suggest that some neolignans might be valuable antitumor promoters or chemopreventors.

Kadsutherin D, a new dibenzocyclooctadiene lignan from Kadsura species.[Pubmed:19023792]

Nat Prod Res. 2008;22(15):1344-9.

A new dibenzocyclooctadiene lignan, kadsutherin D (1), together with 12 known lignans, kadsurin (2), heteroclitin C (3), Interiotherin C (4), schisanlignone A (5), binankadsurin A (6), angeloyl binankadsurin A (7), gomisin U (8), heteroclitin D (9), interiorin (10), schiarisanrin C (11), heteroclitin G (12) and meso-dihydroguaiaretic acid (13) were isolated from the stems of Kadsura species. Their structures were elucidated by spectroscopic methods including 2D-NMR techniques.

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