Gnemonol BCAS# 462636-74-4 |
Quality Control & MSDS
3D structure
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| Cas No. | 462636-74-4 | SDF | Download SDF |
| PubChem ID | 16148652 | Appearance | Powder |
| Formula | C56H42O12 | M.Wt | 907.0 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5-[(2S,3S)-4-hydroxy-6-[(2S,3S)-4-hydroxy-6-[(2S,3S)-4-hydroxy-2-(4-hydroxyphenyl)-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuran-3-yl]benzene-1,3-diol | ||
| SMILES | C1=CC(=CC=C1C=CC2=CC3=C(C(C(O3)C4=CC=C(C=C4)O)C5=CC6=C(C(C(O6)C7=CC=C(C=C7)O)C8=CC9=C(C(C(O9)C1=CC=C(C=C1)O)C1=CC(=CC(=C1)O)O)C(=C8)O)C(=C5)O)C(=C2)O)O | ||
| Standard InChIKey | ZVULRZLKHBBDMD-UXGYSEAKSA-N | ||
| Standard InChI | InChI=1S/C56H42O12/c57-36-11-3-28(4-12-36)1-2-29-19-42(63)51-45(20-29)66-55(31-7-15-38(59)16-8-31)49(51)34-23-44(65)53-47(25-34)68-56(32-9-17-39(60)18-10-32)50(53)35-24-43(64)52-46(26-35)67-54(30-5-13-37(58)14-6-30)48(52)33-21-40(61)27-41(62)22-33/h1-27,48-50,54-65H/b2-1+/t48-,49-,50-,54+,55+,56+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Gnetum montanum
| Description | 1. Gnemonol B exhibits strong antibacterial activity against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). |
| Targets | Antifection |
Gnemonol B Dilution Calculator
Gnemonol B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.1025 mL | 5.5127 mL | 11.0254 mL | 22.0507 mL | 27.5634 mL |
| 5 mM | 0.2205 mL | 1.1025 mL | 2.2051 mL | 4.4101 mL | 5.5127 mL |
| 10 mM | 0.1103 mL | 0.5513 mL | 1.1025 mL | 2.2051 mL | 2.7563 mL |
| 50 mM | 0.0221 mL | 0.1103 mL | 0.2205 mL | 0.441 mL | 0.5513 mL |
| 100 mM | 0.011 mL | 0.0551 mL | 0.1103 mL | 0.2205 mL | 0.2756 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antibacterial activity of stilbene oligomers against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) and their synergism with antibiotics.[Pubmed:17408003]
Biocontrol Sci. 2007 Mar;12(1):7-14.
Two resveratrol trimers, Gnemonol B isolated from Gnetum gnemon and gnetin E obtained from the Gnetum species, were found to exhibit strong antibacterial activities against vancomycin-resistant Enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). The MIC values of Gnemonol B against five strains of VRE and nine strains of MRSA were 12.5 and 6.25 microg/ml, respectively. The MIC values of gnetin E against five strains of VRE and nine strains of MRSA ranged from 12.5 to 25microg/ml. These compounds also showed synergistic effects when used in combination with commercially available antibiotics according to the evaluation method using FIC indices. These findings suggested that the application of the test compounds alone or in combination with antibiotics might be useful in controlling and treating VRE and MRSA infections
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