Gnetumontanin BCAS# 809237-87-4 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 809237-87-4 | SDF | Download SDF |
| PubChem ID | 102004602 | Appearance | Powder |
| Formula | C42H32O11 | M.Wt | 712.7 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 4-[(2S,3S)-3-(3,5-dihydroxyphenyl)-7-[(2S,3S)-3-(3,5-dihydroxyphenyl)-4-hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]-4-hydroxy-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol | ||
| SMILES | C1=CC(=CC=C1C=CC2=CC3=C(C(C(O3)C4=C5C(=C(C=C4)O)C(C(O5)C6=C(C=C(C=C6)O)O)C7=CC(=CC(=C7)O)O)C8=CC(=CC(=C8)O)O)C(=C2)O)O | ||
| Standard InChIKey | RSCPVPKROFWCSQ-QMPRLUHESA-N | ||
| Standard InChI | InChI=1S/C42H32O11/c43-24-5-3-20(4-6-24)1-2-21-11-34(51)38-35(12-21)52-41(36(38)22-13-26(45)17-27(46)14-22)31-9-10-32(49)39-37(23-15-28(47)18-29(48)16-23)40(53-42(31)39)30-8-7-25(44)19-33(30)50/h1-19,36-37,40-41,43-51H/b2-1+/t36-,37-,40+,41+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Gnetumontanin B shows potent inhibition of TNF-alpha. |
| Targets | TNF-α |
| Structure Identification | Planta Med. 2004 Feb;70(2):160-5.Four new stilbenoids from the lianas of Gnetum montanum f. megalocarpum.[Pubmed: 14994195]
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Gnetumontanin B Dilution Calculator
Gnetumontanin B Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4031 mL | 7.0156 mL | 14.0311 mL | 28.0623 mL | 35.0779 mL |
| 5 mM | 0.2806 mL | 1.4031 mL | 2.8062 mL | 5.6125 mL | 7.0156 mL |
| 10 mM | 0.1403 mL | 0.7016 mL | 1.4031 mL | 2.8062 mL | 3.5078 mL |
| 50 mM | 0.0281 mL | 0.1403 mL | 0.2806 mL | 0.5612 mL | 0.7016 mL |
| 100 mM | 0.014 mL | 0.0702 mL | 0.1403 mL | 0.2806 mL | 0.3508 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Four new stilbenoids from the lianas of Gnetum montanum f. megalocarpum.[Pubmed:14994195]
Planta Med. 2004 Feb;70(2):160-5.
From the lianas of Gnetum montanum Markgr. f. megalocarpum Markgr., four new stilbenoids, gnetumontanins A - D ( 1 - 4) were obtained together with 16 known compounds. Gnetumontanin A ( 1) is the first oligostilbene dimerized from two oxyresveratrol units, Gnetumontanin B ( 2) is a new stilbene trimer oligomerized from two oxyresveratrol and one resveratrol units, gnetumontanin C ( 3) is a new stilbenoid with a novel skeleton having a delta-lactone moiety and gnetumontanin D ( 4) is a glucoside of 3. Their structures were determined by means of spectroscopic evidence, especially 2D NMR techniques. Gnetumontanin B showed potent inhibition of TNF-alpha with an inhibitory ratio of 58.1 % (P < 0.05) at a concentration of 10 ( - 5) mol L (-1) and the IC (50) was 1.49 x 10 ( - 6) mol L (-1).
