Tectorigenin sodium sulfonateCAS# 807636-25-5 |
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| Cas No. | 807636-25-5 | SDF | Download SDF |
| PubChem ID | 23667944 | Appearance | Powder |
| Formula | C16H11NaO9S | M.Wt | 402.3 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | sodium;5-(5,7-dihydroxy-6-methoxy-4-oxochromen-3-yl)-2-hydroxybenzenesulfonate | ||
| SMILES | COC1=C(C=C2C(=C1O)C(=O)C(=CO2)C3=CC(=C(C=C3)O)S(=O)(=O)[O-])O.[Na+] | ||
| Standard InChIKey | HTQBVSXOJWIXNI-UHFFFAOYSA-M | ||
| Standard InChI | InChI=1S/C16H12O9S.Na/c1-24-16-10(18)5-11-13(15(16)20)14(19)8(6-25-11)7-2-3-9(17)12(4-7)26(21,22)23;/h2-6,17-18,20H,1H3,(H,21,22,23);/q;+1/p-1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Tectorigenin sodium sulfonate has antioxidant activity. |
Tectorigenin sodium sulfonate Dilution Calculator
Tectorigenin sodium sulfonate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4857 mL | 12.4285 mL | 24.8571 mL | 49.7141 mL | 62.1427 mL |
| 5 mM | 0.4971 mL | 2.4857 mL | 4.9714 mL | 9.9428 mL | 12.4285 mL |
| 10 mM | 0.2486 mL | 1.2429 mL | 2.4857 mL | 4.9714 mL | 6.2143 mL |
| 50 mM | 0.0497 mL | 0.2486 mL | 0.4971 mL | 0.9943 mL | 1.2429 mL |
| 100 mM | 0.0249 mL | 0.1243 mL | 0.2486 mL | 0.4971 mL | 0.6214 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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In vitro evaluation of tectoridin, tectorigenin and tectorigenin sodium sulfonate on antioxidant properties.[Pubmed:22079309]
Food Chem Toxicol. 2012 Feb;50(2):409-14.
Tectoridin (4',5,7-thrihydroxy-6-methoxyisoflavone-7-O-beta-d-glucopyranoside) isolated from the flowers of Pueraria thunbergiana is reported to have less hepatoprotective, hypoglycemic, antiallergic and anaphylaxis inhibitory activity than its aglycone form tectorigenin. To obtain tectorigenin, tectoridin was hydrolyzed in the current study. However, practical limitations of tectorigenin do exist due to its poor water-solubility. To increase its water-solubility, tectorigenin was sulfonated with sulfuric acid (98wt.%) and mixed with saturated salt water to produce Tectorigenin sodium sulfonate. Tectoridin and the two transfer products were identified by UV, IR, HPLC-MS, (1)H NMR and (13)C NMR, and the solubility of Tectorigenin sodium sulfonate was increased about 9-fold than tectorigenin. Antioxidant experiments of tectoridin, tectorigenin and modified tectorigenin in vitro including reducing power, superoxide anion radical scavenging activity, hydroxyl radical scavenging activity, 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging activity and anti-lipid peroxidation were carried on comparing with ascorbic acid (Vc) or butylated hydroxytoluene (BHT). The results suggested that the antioxidant activity in all the experimental systems exhibited the same order as follows: Tectorigenin sodium sulfonate>tectorigenin>tectoridin. Due to the high water-solubility and good antioxidant properties with Tectorigenin sodium sulfonate, appropriate chemical modifications could greatly improve the biological activities of the naturally occurring products.
