Gnetin D

CAS# 84870-53-1

Gnetin D

2D Structure

Catalog No. BCN3380----Order now to get a substantial discount!

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Gnetin D: 5mg $828 In Stock
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Quality Control of Gnetin D

3D structure

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Gnetin D

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Chemical Properties of Gnetin D

Cas No. 84870-53-1 SDF Download SDF
PubChem ID 102004736 Appearance Powder
Formula C28H22O7 M.Wt 470.5
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[(2S,3S)-3-(3,5-dihydroxyphenyl)-6-hydroxy-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-2-yl]benzene-1,3-diol
SMILES C1=CC(=CC=C1C=CC2=CC(=CC3=C2C(C(O3)C4=C(C=C(C=C4)O)O)C5=CC(=CC(=C5)O)O)O)O
Standard InChIKey KYXFGKLZVUDIIX-BQYFGGCBSA-N
Standard InChI InChI=1S/C28H22O7/c29-18-5-2-15(3-6-18)1-4-16-9-22(33)14-25-26(16)27(17-10-20(31)12-21(32)11-17)28(35-25)23-8-7-19(30)13-24(23)34/h1-14,27-34H/b4-1+/t27-,28+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Gnetin D

The herbs of Gnetum cleistostachynm

Biological Activity of Gnetin D

Description1. Gnetin D exhibits significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99  ug/mL.
TargetsInfluenza virus

Gnetin D Dilution Calculator

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Gnetin D Molarity Calculator

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Preparing Stock Solutions of Gnetin D

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1254 mL 10.627 mL 21.254 mL 42.508 mL 53.135 mL
5 mM 0.4251 mL 2.1254 mL 4.2508 mL 8.5016 mL 10.627 mL
10 mM 0.2125 mL 1.0627 mL 2.1254 mL 4.2508 mL 5.3135 mL
50 mM 0.0425 mL 0.2125 mL 0.4251 mL 0.8502 mL 1.0627 mL
100 mM 0.0213 mL 0.1063 mL 0.2125 mL 0.4251 mL 0.5313 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Gnetin D

In vitro anti-influenza viral activities of stilbenoids from the lianas of Gnetum pendulum.[Pubmed:20539973]

Planta Med. 2010 Nov;76(16):1874-6.

The anti-influenza viral activities of six stilbenoids from the lianas of Gnetum pendulum C. Y. Cheng were evaluated with two different assays, neuraminidase (NA) activity assay and cytopathic effect (CPE) reduction assay. The NA assay results showed that all six stilbenoids exerted an NA inhibitory effect, while the CPE assay indicated that among them, isorhapontigenin (2), gnetupendin B (3), shegansu B (4), and Gnetin D 6) exhibit significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 microg/mL in comparison to the positive controls oseltamivir acid and ribavirin whose IC(50) values were 0.040 and 5.54 microg/mL, respectively.

Secondary metabolites from Spirotropis longifolia (DC) Baill and their antifungal activity against human pathogenic fungi.[Pubmed:22137037]

Phytochemistry. 2012 Feb;74:166-72.

A phytochemical study of the ethyl acetate extract of the roots and adventitious roots of Spirotropis longifolia, a monodominant tree species of the Guianan rainforest, has allowed the isolation of three compounds: 2-hydroxy-8,9-methylenedioxy-2',2'-dimethylpyrano-[5',6':4,3]-6a-prenyl-[6aS,11aS ]-pterocarpan (spirotropin A), 2-hydroxy-8,9-methylenedioxy-2',2'-dimethyl-3',4'-dihydropyrano-[5',6':4,3]-6a-pr enyl-[6aS,11aS]-pterocarpan (spirotropin B), and 5,7-dihydroxy-6,8-diprenyl-2'''',2''''-dimethylpyrano[5'''',6'''': 3',4']-isoflavone (spirotropone). In addition, 10 known compounds, trans-oxyresveratrol, trans-resveratrol, piceatannol, daidzein, genistein, isoprunetin, lupeol, latifolol, Gnetin D and gnetin E, were also isolated. These compounds were evaluated for their antifungal activity and their cytotoxicity, and their structures were established by 1D and 2D NMR, HRMS, CD and optical rotation measurements.

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