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Stigmasta-4,25-dien-3-one

CAS# 848669-08-9

Stigmasta-4,25-dien-3-one

Catalog No. BCN4395----Order now to get a substantial discount!

Product Name & Size Price Stock
Stigmasta-4,25-dien-3-one: 5mg Please Inquire In Stock
Stigmasta-4,25-dien-3-one: 10mg Please Inquire In Stock
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Quality Control of Stigmasta-4,25-dien-3-one

Number of papers citing our products

Chemical structure

Stigmasta-4,25-dien-3-one

3D structure

Chemical Properties of Stigmasta-4,25-dien-3-one

Cas No. 848669-08-9 SDF Download SDF
PubChem ID 71307334 Appearance Powder
Formula C29H46O M.Wt 410.7
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylhept-6-en-2-yl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
SMILES CCC(CCC(C)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)C(=C)C
Standard InChIKey IUJSEAGAJKMVBJ-XJZKHKOHSA-N
Standard InChI InChI=1S/C29H46O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h18,20-21,24-27H,2,7-17H2,1,3-6H3/t20-,21-,24+,25-,26+,27+,28+,29-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Stigmasta-4,25-dien-3-one

The herbs of Porcelia macrocarpa

Biological Activity of Stigmasta-4,25-dien-3-one

In vitro

New α-Glucosidase Inhibitory Triterpenic Acid from Marine Macro Green Alga Codium dwarkense Boergs.[Reference: WebLink]

Marine Drugs, 2015, 13(7):4344-4356.

The marine ecosystem has been a key resource for secondary metabolites with promising biological roles.
METHODS AND RESULTS:
In the current study, bioassay-guided phytochemical investigations were carried out to assess the presence of enzyme inhibitory chemical constituents from the methanolic extract of marine green alga-Codium dwarkense. The bioactive fractions were further subjected to chromatographic separations, which resulted in the isolation of a new triterpenic acid; dwarkenoic acid (1) and the known sterols; androst-5-en-3β-ol (2), stigmasta-5,25-dien-3β,7α-diol (3), ergosta-5,25-dien-3β-ol (4), 7-hydroxyStigmasta-4,25-dien-3-one-7-O-β-d-fucopyranoside (5), 7-hydroxyStigmasta-4,25-dien-3-one (6), and stigmasta-5,25-dien-3β-ol (7). The structure elucidation of the new compound was carried out by combined mass spectrometry and 1D (1H and 13C) and 2D (HSQC, HMBC, COSY, and NOESY) NMR spectroscopic data. The sub-fractions and pure constituents were assayed for enzymatic inhibition of alpha-glucosidase.
CONCLUSIONS:
Compound 1 showed significant inhibition at all concentrations. Compounds 2, 3, 5, and 7 exhibited a dose-dependent response, whereas compounds 4-6 showed moderate inhibition. Utilizing such marine-derived biological resources could lead to drug discoveries related to anti-diabetics.

Stigmasta-4,25-dien-3-one Dilution Calculator

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Stigmasta-4,25-dien-3-one Molarity Calculator

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Preparing Stock Solutions of Stigmasta-4,25-dien-3-one

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4349 mL 12.1743 mL 24.3487 mL 48.6973 mL 60.8717 mL
5 mM 0.487 mL 2.4349 mL 4.8697 mL 9.7395 mL 12.1743 mL
10 mM 0.2435 mL 1.2174 mL 2.4349 mL 4.8697 mL 6.0872 mL
50 mM 0.0487 mL 0.2435 mL 0.487 mL 0.9739 mL 1.2174 mL
100 mM 0.0243 mL 0.1217 mL 0.2435 mL 0.487 mL 0.6087 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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