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Glaucogenin C mono-D-thevetoside

CAS# 849201-84-9

Glaucogenin C mono-D-thevetoside

Catalog No. BCN7089----Order now to get a substantial discount!

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Glaucogenin C mono-D-thevetoside: 5mg $1098 In Stock
Glaucogenin C mono-D-thevetoside: 10mg Please Inquire In Stock
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Quality Control of Glaucogenin C mono-D-thevetoside

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Chemical structure

Glaucogenin C mono-D-thevetoside

3D structure

Chemical Properties of Glaucogenin C mono-D-thevetoside

Cas No. 849201-84-9 SDF Download SDF
PubChem ID 21632986 Appearance Powder
Formula C28H40O9 M.Wt 520.61
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4S,5R,8S,13R,16S,19R,22R)-8-[(2R,3R,4S,5R,6R)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5,19-dimethyl-15,18,20-trioxapentacyclo[14.5.1.04,13.05,10.019,22]docosa-1(21),10-dien-14-one
SMILES CC1C(C(C(C(O1)OC2CCC3(C4CCC5=COC6(C5C(CO6)OC(=O)C4CC=C3C2)C)C)O)OC)O
Standard InChIKey KBZJWPGSJWUHPT-FJUGQGNPSA-N
Standard InChI InChI=1S/C28H40O9/c1-14-22(29)24(32-4)23(30)26(35-14)36-17-9-10-27(2)16(11-17)6-7-18-19(27)8-5-15-12-33-28(3)21(15)20(13-34-28)37-25(18)31/h6,12,14,17-24,26,29-30H,5,7-11,13H2,1-4H3/t14-,17+,18-,19+,20-,21-,22-,23-,24+,26+,27+,28+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Glaucogenin C mono-D-thevetoside

The roots of Cynanchum stauntonii.

Biological Activity of Glaucogenin C mono-D-thevetoside

DescriptionGlaucogenin C mono-D-thevetoside is a natural product from Cynanchum stauntonii.

Protocol of Glaucogenin C mono-D-thevetoside

Structure Identification
Planta Med. 2004 Nov;70(11):1075-9.

Steroids from the roots of Cynanchum stauntonii.[Pubmed: 15549665 ]


METHODS AND RESULTS:
A chemical investigation of the roots of Cynanchum stauntonii has resulted in the characterization of a new hydroperoxide with a 13,14 : 14,15-disecopregnane-type skeleton, named stauntonine (1), together with three related compounds, anhydrohirundigenin (2), anhydrohirundigenin monothevetoside (3), and Glaucogenin C mono-D-thevetoside(4). Their structures were established by spectroscopic methods, including X-ray crystallographic diffraction analysis of stauntonine that confirmed its relative stereochemistry.
CONCLUSIONS:
The compound 1 showed dose-dependent relaxation on aortic rings with endothelium contracted by phenylepherine or KCl.

Glaucogenin C mono-D-thevetoside Dilution Calculator

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Glaucogenin C mono-D-thevetoside Molarity Calculator

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Preparing Stock Solutions of Glaucogenin C mono-D-thevetoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9208 mL 9.6041 mL 19.2082 mL 38.4165 mL 48.0206 mL
5 mM 0.3842 mL 1.9208 mL 3.8416 mL 7.6833 mL 9.6041 mL
10 mM 0.1921 mL 0.9604 mL 1.9208 mL 3.8416 mL 4.8021 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7683 mL 0.9604 mL
100 mM 0.0192 mL 0.096 mL 0.1921 mL 0.3842 mL 0.4802 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Glaucogenin C mono-D-thevetoside

Steroids from the roots of Cynanchum stauntonii.[Pubmed:15549665]

Planta Med. 2004 Nov;70(11):1075-9.

A chemical investigation of the roots of Cynanchum stauntonii has resulted in the characterization of a new hydroperoxide with a 13,14 : 14,15-disecopregnane-type skeleton, named stauntonine (1), together with three related compounds, anhydrohirundigenin (2), anhydrohirundigenin monothevetoside (3), and glaucogenin-C mono- D-thevetoside (4). Their structures were established by spectroscopic methods, including X-ray crystallographic diffraction analysis of stauntonine that confirmed its relative stereochemistry. The compound 1 showed dose-dependent relaxation on aortic rings with endothelium contracted by phenylepherine or KCl.

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