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6-O-benzoylgomisin O

CAS# 130783-32-3

6-O-benzoylgomisin O

2D Structure

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3D structure

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6-O-benzoylgomisin O

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Chemical Properties of 6-O-benzoylgomisin O

Cas No. 130783-32-3 SDF Download SDF
PubChem ID 91826818 Appearance Cryst.
Formula C30H32O8 M.Wt 520.6
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4C(C1C)OC(=O)C5=CC=CC=C5)OC)OC)OC)OC)OCO3
Standard InChIKey XUGSROZUUURBSW-XOWTYJCDSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 6-O-benzoylgomisin O

The seeds of Schisandra chinensis (Turcz.) Baill.

Biological Activity of 6-O-benzoylgomisin O

Description6-O-benzoylgomisin O is a natural product from Schisandra sphenanthera.

Protocol of 6-O-benzoylgomisin O

Structure Identification
Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(11):1597-601.

Chemical constituents of petroleum ether extract of fruits of Schisandra sphenanthera.[Pubmed: 22993989]

To study the chemical constituents in the fruits of Schisandra sphenanthera.
METHODS AND RESULTS:
The constituents were isolated by their silica gel column, Sephadex LH-20 gel column, and their structures were elucidated by their chemical properties and spectroscopic analyses. Twelve compounds were isolated and identified as (+)-anwulignan (1), deoxyschizandrin (2), interiotherin A (3), schisantherin A (4), beta-sitosterol (5), schisantherin D (6), 4-hydroxybenzaldehyde (7), 6-O-benzoylgomisin O (8), schizandronic acid (9), schisanlactone D (10), schisanlactone B (11), kadsulactone A (12).
CONCLUSIONS:
Compounds 3, 7, 10-12 were obtained from this plant for the first time.

6-O-benzoylgomisin O Dilution Calculator

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Preparing Stock Solutions of 6-O-benzoylgomisin O

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9209 mL 9.6043 mL 19.2086 mL 38.4172 mL 48.0215 mL
5 mM 0.3842 mL 1.9209 mL 3.8417 mL 7.6834 mL 9.6043 mL
10 mM 0.1921 mL 0.9604 mL 1.9209 mL 3.8417 mL 4.8022 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7683 mL 0.9604 mL
100 mM 0.0192 mL 0.096 mL 0.1921 mL 0.3842 mL 0.4802 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 6-O-benzoylgomisin O

[Chemical constituents of petroleum ether extract of fruits of Schisandra sphenanthera].[Pubmed:22993989]

Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(11):1597-601.

OBJECTIVE: To study the chemical constituents in the fruits of Schisandra sphenanthera. METHOD: The constituents were isolated by their silica gel column, Sephadex LH-20 gel column, and their structures were elucidated by their chemical properties and spectroscopic analyses. RESULT: Twelve compounds were isolated and identified as (+)-anwulignan (1), deoxyschizandrin (2), interiotherin A (3), schisantherin A (4), beta-sitosterol (5), schisantherin D (6), 4-hydroxybenzaldehyde (7), 6-O-benzoylgomisin O (8), schizandronic acid (9), schisanlactone D (10), schisanlactone B (11), kadsulactone A (12). CONCLUSION: Compounds 3, 7, 10-12 were obtained from this plant for the first time.

Description

Benzoylgomisin O isolated from Schisandra rubriflora, has inhibitory activity against 15-LOX, COX-1 and COX-2 enzymes and anti-inflammatory activity.

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