Schizanrin L

CAS# 874472-16-9

Schizanrin L

Catalog No. BCN3620----Order now to get a substantial discount!

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Quality Control of Schizanrin L

Number of papers citing our products

Chemical structure

Schizanrin L

3D structure

Chemical Properties of Schizanrin L

Cas No. 874472-16-9 SDF Download SDF
PubChem ID 102004694 Appearance Cryst.
Formula C31H36O8 M.Wt 536.6
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3C(C1C)OC(=O)C4=CC=CC=C4)OC)OC)OC)OC)OC)OC
Standard InChIKey WYLGJYYEEZHUJZ-UHFFFAOYSA-N
Standard InChI InChI=1S/C31H36O8/c1-17-14-20-15-22(33-3)27(35-5)29(37-7)24(20)25-21(16-23(34-4)28(36-6)30(25)38-8)26(18(17)2)39-31(32)19-12-10-9-11-13-19/h9-13,15-18,26H,14H2,1-8H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Schizanrin L

The herbs of Kadsura coccinea

Biological Activity of Schizanrin L

DescriptionSchizanrin L is a natural product from Kadsura coccinea.
In vitro

Antihepatitis activity (anti-HBsAg and anti-HBeAg) of C19 homolignans and six novel C18 dibenzocyclooctadiene lignans from Kadsura japonica.[Pubmed: 16041651 ]

Planta Med. 2005 Jul;71(7):646-53.


METHODS AND RESULTS:
Bioassay-directed fractionation of the EtOAc extract of Kadsura japonica has led to the isolation of six new C18 dibenzocyclooctadiene lignans, schizanrin I, schizanrin J, schizanrin K, Schizanrin L, schizanrin M, schizanrin N, along with four known C19 homolignans, taiwanschirins A, B, C, and heteroclitin F. The elucidations of the new structures were based on spectral analysis.
CONCLUSIONS:
Bioassay evaluation against human type B hepatitis revealed that taiwanschirins A and B showed strong activity for anti-HBsAg and a medium effect for anti-HBeAg at 25 microg/mL (12.9 and 11.9 microM for taiwanschirins A and B, respectively).

Schizanrin L Dilution Calculator

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Schizanrin L Molarity Calculator

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Preparing Stock Solutions of Schizanrin L

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8636 mL 9.3179 mL 18.6359 mL 37.2717 mL 46.5896 mL
5 mM 0.3727 mL 1.8636 mL 3.7272 mL 7.4543 mL 9.3179 mL
10 mM 0.1864 mL 0.9318 mL 1.8636 mL 3.7272 mL 4.659 mL
50 mM 0.0373 mL 0.1864 mL 0.3727 mL 0.7454 mL 0.9318 mL
100 mM 0.0186 mL 0.0932 mL 0.1864 mL 0.3727 mL 0.4659 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Schizanrin L

Antihepatitis activity (anti-HBsAg and anti-HBeAg) of C19 homolignans and six novel C18 dibenzocyclooctadiene lignans from Kadsura japonica.[Pubmed:16041651]

Planta Med. 2005 Jul;71(7):646-53.

Bioassay-directed fractionation of the EtOAc extract of Kadsura japonica has led to the isolation of six new C18 dibenzocyclooctadiene lignans, schizanrins I, J, K, L, M, N, along with four known C19 homolignans, taiwanschirins A, B, C, and heteroclitin F. The elucidations of the new structures were based on spectral analysis. Bioassay evaluation against human type B hepatitis revealed that taiwanschirins A and B showed strong activity for anti-HBsAg and a medium effect for anti-HBeAg at 25 microg/mL (12.9 and 11.9 microM for taiwanschirins A and B, respectively).

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