Glepidotin B

CAS# 87440-56-0

Glepidotin B

Catalog No. BCN4844----Order now to get a substantial discount!

Product Name & Size Price Stock
Glepidotin B: 5mg $828 In Stock
Glepidotin B: 10mg Please Inquire In Stock
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Quality Control of Glepidotin B

Number of papers citing our products

Chemical structure

Glepidotin B

3D structure

Chemical Properties of Glepidotin B

Cas No. 87440-56-0 SDF Download SDF
PubChem ID 442411 Appearance Powder
Formula C20H20O5 M.Wt 340.4
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3R)-3,5,7-trihydroxy-8-(3-methylbut-2-enyl)-2-phenyl-2,3-dihydrochromen-4-one
SMILES CC(=CCC1=C(C=C(C2=C1OC(C(C2=O)O)C3=CC=CC=C3)O)O)C
Standard InChIKey ATJOIGKHVRPLSM-RBUKOAKNSA-N
Standard InChI InChI=1S/C20H20O5/c1-11(2)8-9-13-14(21)10-15(22)16-17(23)18(24)19(25-20(13)16)12-6-4-3-5-7-12/h3-8,10,18-19,21-22,24H,9H2,1-2H3/t18-,19+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Glepidotin B

The roots of Glycyrrhiza lepidota

Biological Activity of Glepidotin B

In vitro

Isolation of an anti-HIV diprenylated bibenzyl from Glycyrrhiza lepidota.[Pubmed: 11524125]

Phytochemistry. 2001 Sep;58(1):153-7.


METHODS AND RESULTS:
The organic soluble extract from the leaves of Glycyrrhiza lepidota showed moderate activity in the US National Cancer Institute in vitro anti-HIV-1 bioassay. Chromatographic separation of this extract resulted in the identification of a new diprenylated bibenzyl as the compound responsible for the observed anti-viral activity. Extensive spectroscopic experiments provide the complete 1H NMR and 13C NMR spectral assignments to support the proposed structure.
CONCLUSIONS:
Known compounds Glepidotin B and glepidotin A were also isolated from the extract and shown to be inactive in the anti-viral assay.

Glepidotin B Dilution Calculator

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Glepidotin B Molarity Calculator

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Preparing Stock Solutions of Glepidotin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9377 mL 14.6886 mL 29.3772 mL 58.7544 mL 73.443 mL
5 mM 0.5875 mL 2.9377 mL 5.8754 mL 11.7509 mL 14.6886 mL
10 mM 0.2938 mL 1.4689 mL 2.9377 mL 5.8754 mL 7.3443 mL
50 mM 0.0588 mL 0.2938 mL 0.5875 mL 1.1751 mL 1.4689 mL
100 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.5875 mL 0.7344 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Glepidotin B

Isolation of an anti-HIV diprenylated bibenzyl from Glycyrrhiza lepidota.[Pubmed:11524125]

Phytochemistry. 2001 Sep;58(1):153-7.

The organic soluble extract from the leaves of Glycyrrhiza lepidota showed moderate activity in the US National Cancer Institute in vitro anti-HIV-1 bioassay. Chromatographic separation of this extract resulted in the identification of a new diprenylated bibenzyl as the compound responsible for the observed anti-viral activity. Extensive spectroscopic experiments provide the complete 1H NMR and 13C NMR spectral assignments to support the proposed structure. Known compounds Glepidotin B and glepidotin A were also isolated from the extract and shown to be inactive in the anti-viral assay.

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