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3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

CAS# 873867-94-8

3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

Catalog No. BCN7238----Order now to get a substantial discount!

Product Name & Size Price Stock
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 5mg $886 In Stock
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 10mg Please Inquire In Stock
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 20mg Please Inquire Please Inquire
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 50mg Please Inquire Please Inquire
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 100mg Please Inquire Please Inquire
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 200mg Please Inquire Please Inquire
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 500mg Please Inquire Please Inquire
3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan: 1000mg Please Inquire Please Inquire

Quality Control of 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

Number of papers citing our products

Chemical structure

3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

3D structure

Chemical Properties of 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

Cas No. 873867-94-8 SDF Download SDF
PubChem ID 100854209 Appearance Powder
Formula C22H24O7 M.Wt 400.42
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-[(3S,3aR,6R,6aR)-3-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-4-methoxy-1,3-benzodioxole
SMILES COC1=C(C=C(C=C1)C2C3COC(C3CO2)C4=CC5=C(C(=C4)OC)OCO5)OC
Standard InChIKey UTPBMRNHPNUBLT-YJPXFSGGSA-N
Standard InChI InChI=1S/C22H24O7/c1-23-16-5-4-12(6-17(16)24-2)20-14-9-27-21(15(14)10-26-20)13-7-18(25-3)22-19(8-13)28-11-29-22/h4-8,14-15,20-21H,9-11H2,1-3H3/t14-,15-,20+,21-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

The roots of Artemisia absinthium.

Biological Activity of 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

In vitro

A New Larvicidal Lignan from Piper fimbriulatum.[Reference: WebLink]

Pharmaceutical Biology, 2008, 43(4):378-381.


METHODS AND RESULTS:
A new lignan, 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan (1) (6-[4-(3,4-dimethoxy-phenyl)-tetrahydro-furo[3,4-c.]furan-1-yl]-4-methoxy-benzo[] dioxole) together with two known lignans, 7′-epi.-sesartemin (2) and diayangambin (3), and a known flavonoid, 5-hydroxy-7,4′-dimethoxyflavone (4), were isolated from the leaves of Piper fimbriulatum. C. DC. Their structures were assigned by a combination of one- and two-dimensional NMR techniques.
CONCLUSIONS:
7′-epi.-Sesartemin (2) showed the highest larvicidal activity against Aedes aegypti. (LC100 17.6 µg/ml) and weak antiplasmodial (IC50 7.0 µg/ml) and antitrypanosomal (IC50 39.0 µg/ml) activities. None of the compounds was active against Leishmania mexicana..

3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan Dilution Calculator

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3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan Molarity Calculator

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Preparing Stock Solutions of 3,4,5'-Trimethoxy-3',4'-methylenedioxy-7,9':7',9-diepoxylignan

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4974 mL 12.4869 mL 24.9738 mL 49.9476 mL 62.4344 mL
5 mM 0.4995 mL 2.4974 mL 4.9948 mL 9.9895 mL 12.4869 mL
10 mM 0.2497 mL 1.2487 mL 2.4974 mL 4.9948 mL 6.2434 mL
50 mM 0.0499 mL 0.2497 mL 0.4995 mL 0.999 mL 1.2487 mL
100 mM 0.025 mL 0.1249 mL 0.2497 mL 0.4995 mL 0.6243 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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