Products with Insulin-stimulated action bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1215 | Chicoric acid |
| Chicoric acid, a new compound able to enhance insulin release and glucose uptake, it is a new potential antidiabetic agent carrying both insulin sensitizing and insulin-secreting properties. Chicoric acid has antiobesity effects, it can induce apoptosis in 3T3-L1 preadipocytes through ROS-mediated PI3K/Akt and MAPK signaling pathways. L-Chicoric acid has antiviral activity against HIV-1, which has been attributed to the inhibition of HIV-1 integration. | |
| BCN1241 | (-)-Licarin B |
| Licarin B can improve insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes, it as a promising bioactive for insulin resistance and associated complications through its partial PPARγ activity. | |
| BCN2186 | Vitamin D3 |
| Vitamin D3 is a form of vitamin D, binds and activates a H305F/H397Y mutant vitamin D receptor (VDR) with EC50 of 300 nM. Supplemental calcium and Vitamin D3 may increase TGFβ1 expression and shift TGFα expression downward from the differentiation to the proliferation zone in the crypts in the normal-appearing colorectal mucosa of sporadic colorectal adenoma patients. | |
| BCN2578 | Mogroside VI |
| 1. Lo Han Kuo extract is a high intensive sweetening agent with desirable health benefits, such as prevention of dental caries through specific antibacterial properties, no-calorie levels related to obesity, and a low glycemic index to help manage blood sugar levels in diabetic patients;mogrosides have the antimicrobial activity and the insulin-stimulating activity, this includes mogroside I, II, III, IV, V, mogroside VI, 11-o-Mogroside V, and Siamenoside I, siraitiflavandiol, rhamnocitrin-3-O-rhamnoside, and kaempferitrin that are the functional groups in these antimicrobial and insulin secretion activities. | |
| BCN2640 | Cycloart-23-ene-3,25-diol |
| 1. Cycloart-23-ene-3,25-diol has anti-inflammatory activity . 2. Cycloart-23-ene-3,25-diol has protective activity against streptozotocin induced toxicity. 3. Cycloart-23-ene-3,25-diol treatment can decrease liver malondialdehyde but increase superoxidase dismutase and reduced glutathione. | |
