Products with Precursors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5789 | Matairesinol |
| Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α in hypoxic HeLa cells.Matairesinol has anti-osteoporotic activity via p38/ERK-NFATc1 signaling, but not by way of anti-resorptive action. Matairesinol could markedly benefit TRAIL-based tumor therapies, including those aimed at prostate cancer. | |
| BCN5949 | Polydatin |
| Polydatin has antioxidant, anti-inflammatory, neuroprotection and anti-cancer activities, which has favorable potency to develop a hypolipemic and/or hepatoprotective agent in clinic. It is a mitochondria protector for acute severe hemorrhagic shock treatment, the neuronal mitochondrial injury is involved in the genesis of severe shock. Polydatin has a protective effect against ischemia/reperfusion injury in rat heart, the cardioprotection of polydatin is mainly mediated by cNOS which leading to an increase in NO production. | |
| BCN5999 | Nyasicol |
| 1. Nyasicol is a precursor of interjectin. | |
| BCN6015 | 3-(hydroxymethyl)cyclopentanone |
| 1. 3-Hydroxymethylcyclopentanone is a precursor to synthesize methyl epijasmonate. 2. 3-Hydroxymethylcyclopentanone compounds, which are useful as intermediates in the preparation of HIV chemokine CCR-5 receptor antagonists. | |
| BCN6200 | Shikimic acid |
| Shikimic acid(Shikimate), more commonly known as its anionic form shikimate, is an important biochemical intermediate in plants and microorganisms, has great potential for the design and synthesis of enzyme inhibitors. It reversed the H2O2 induced oxidative damage in hepatocytes, probably through the inhibition of NF-κB, with the activation of PI3K/Akt/Nrf2 pathway and reduction of apoptosis by interfering the SAPK/JNK/Bax pathway; it also profoundly inhibited pancreatic lipase activity by 66%, thus providing another valuable therapeutic aspect for treating diet induced obesity in humans. | |
