Products with Skin-whitening agents bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4890 | 3,4-Dimethoxyphenol |
| 3,4-Dimethoxyphenol has antimicrobial activity; it also has inhibition of melanin synthesis, it may be used as whitening agents in cosmetics. | |
| BCN5028 | Ethyl 4-methoxycinnamate |
| Ethyl p-methoxycinnamate(Ethyl 4-methoxycinnamate) has antifungal activity, it can inhibit the growth of Trichophyton rubrum, Aspergillus niger, Saccharomyces cerevisiae and Epidermophyton floccosum at a concentration less than 10 mug/ml. Ethyl-p-methoxycinnamate has anti-inflammatory, it can dose-dependently inhibit carrageenan-induced edema with an MIC of 100 mg/kg, and non-selectively inhibit the activities of cyclooxygenases 1 and 2, with IC50 values of 1.12 uM and 0.83 uM respectively; it has chemopreventive activity against fibrosarcoma through inhibition of COX-2, and can block bFGF-induced vessel formation on Matrigel plug assay in vivo. Ethyl p-methoxycinnamate could be developed as a skin whitening agent to treat hyperpigmentary disorders. | |
| BCN5201 | Oxyresveratrol |
| Oxyresveratrol , a dietary phenolic compound, has neuroprotective effect, as a potential nutritional candidate for protection against neurodegeneration in Parkinson disease; Oxyresveratrol has antioxidant activity, can reduce neuronal oxidative damage and protect hepatocytes against oxidative stress and mitochondrial dysfunction, which may be associated with activation of Nrf2, it also as an antibrowning agent for cloudy apple juices and fresh-cut apples. Oxyresveratrol exhibits a potent inhibitory effect on dopa oxidase activity of tyrosinase which catalyzes rate-limiting steps of melanin biosynthesis.Oxyresveratrol exhibits the inhibitory activity at the early and late phase of viral replication and inhibited the viral replication with pretreatment in one-step growth assay of HSV-1 and HSV-2. | |
| BCN5488 | Genkwanin |
| Genkwanin has antitumor, and anti-inflammatory activities, it enhances host immunity, decreases the inflammatory cytokine levels, and regulates the miR-101/MKP-1/MAPK pathway.Genkwanin may have anti-skin ageing activity, it can up-regulate the transcriptional activation of human type vii collagen gene promoter, stimulating the formation of anchoring fibrils at the basement membrane zone in skin contributed to preventing skin ageing; it also induces a decrease of melanin synthesis by inhibiting tyrosinase activity, it could as skin whitening agent in cosmetic preparations. | |
| BCN5516 | Cryptomeridiol |
| 1. (-)-Cryptomeridiol exhibits a significant and concentration-dependent inhibitory effect on PAF receptor binding, with inhibitory concentration (IC)(50) values of 17.5 uM. 2. Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. 3. Cryptomeridiol has low activity against A. niger, T. mentagrophytes, and C. albicans. | |
