Products with Vasoprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1047 | Bilirubin |
| Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism, it is a prominent endogenous antioxidant cytoprotectant and a natural inhibitor of vascular smooth muscle cell proliferation, which has neuroprotective and anti- atherosclerosis-related diseases effects. It can act as an effective agent to reduce mortality and counteract hypotension elicited by endotoxin through mechanisms involving a decreased NOS2 induction secondary to inhibition of NAD(P)H oxidase. | |
| BCN1230 | Cyanidin-3-O-glucoside chloride |
| Cyanidin-3- O -glucoside exhibits strong antioxidant activities, it has protective effects from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure. Cyanidin-3-O-glucoside chloride decreased mutant p21 expression, and increased the ratio of Bax/Bcl-2 and the activation of caspase-3 to induce apoptosis. | |
| BCN1542 | 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol |
| 1. 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol analogs to significantly decrease pulmonary vascular leakage and inflammation in vitro and in vivo. 2. 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propandiol significantly reduces multiple indices of alveolar and vascular permeability in a lipopolysaccharide-mediated murine model of ALI. | |
| BCN1680 | Ginkgolide A |
| Ginkgolide A is a platelet-activating factor antagonist, it can inhibit the neurotoxicity of prions or amyloid-beta1-42, may be relevant treatments for prion or Alzheimer's diseases.Ginkgolide A has neuroprotective, and anxiolytic-like effects, it is widely used for the treatment of cardiovascular diseases and diabetic vascular complications, which might be achieved through regulating the STAT3-mediated pathway. | |
