Natural Products from Cucurbita moschata
Natural Products Isolated from Cucurbita moschata
BioCrick provides high-purity natural products and bioactive compounds isolated and purified from natural sources for scientific research.
- Natural product compounds selected from diverse chemical and biological sources.
- Broad structural diversity and coverage of biological activities.
- Product activity information can be supported by published literature, patents and research reports.
- Natural products can be selected according to source, target, activity and disease research interests.
- Compounds should be stored according to the product specifications after receipt.
Natural Products from Cucurbita moschata
7 natural product s associated with Cucurbita moschata
| Catalog No. | Product Name | CAS Number | COA |
|---|---|---|---|
| BCN8816 |
7,22,25-Stigmastatrienol
|
14485-48-4 | COA |
| BCN8319 |
alpha-Linolenic acid
|
463-40-1 | COA |
| BCN1259 |
D-(+)-Glucose
|
50-99-7 | COA |
| BCN8541 |
DL-Arabinose
|
147-81-9 | COA |
| BCN8471 |
Inositol
|
87-89-8 | COA |
| BCN3821 |
Linoleic acid
|
60-33-3 | COA |
| BCN3820 |
Stearic Acid
|
57-11-4 | COA |
References
Transcriptome analysis reveals the effects of grafting on sugar and α-linolenic acid metabolisms in fruits of cucumber with two different rootstocks.[Pubmed: 30036858]
Flavor quality in cucumber is affected by different rootstocks, but the molecular mechanism is largely unclean. To clarify the differences of sugar and aromatic compounds, cucumber (cucumis sativus) fruits from plants of self-grafted (SG) or grafted onto figleaf gourd (Cucurbita ficifolia; G1) or 'Weisheng No.1' rootstock (Cucurbita moschata ⅹCucurbita moschata hybrids; G2) were performed the transcriptome analysis. We obtained 1013 and 920 differentially expressed genes (DEGs) from G1 and G2 compared to SG respectively, in which 453 genes were co-expressed. Functional annotations showed many DEGs were involved in glycolysis/gluconeogenesis metabolism, fructose metabolism and α-Linolenic acid metabolisms, 20 DEGs were selected from the 3 pathways to validate sequencing accuracy by quantitative real-time PCR. The gene relative expression levels were concurrent with RNA-seq results and sugar and aromatic compounds content phenotypes. Moreover, some vital transcript factors and transport proteins were analyzed. These findings indicate that different rootstocks could induce significantly changes in the physiological profiling and transcripts of sugar- and aromatic flavor-related genes. This study provides a novel insight into the molecular mechanisms of fruit quality regulated by candidate genes.
Dehydrodiconiferyl Alcohol Inhibits Osteoclast Differentiation and Ovariectomy-Induced Bone Loss through Acting as an Estrogen Receptor Agonist.[Pubmed: 29869503]
Estrogen deficiency after menopause increases bone loss by activating RANKL-induced osteoclast differentiation. Dehydrodiconiferyl alcohol (DHCA), a lignan originally isolated from Cucurbita moschata, has been thought to be a phytoestrogen based on its structure. In this study, we tested whether DHCA could affect RANKL-induced osteoclastogenesis in vitro and ovariectomy-induced bone loss in vivo. In RAW264.7 cells, DHCA inhibited RANKL-induced differentiation of osteoclasts. Consistently, expression of the six osteoclastogenic genes induced by RANKL was down-regulated. DHCA was also shown to suppress the NF-κB and p38 MAPK signaling pathways by activating AMPK. Data from transient transfection assays suggested that DHCA might activate the estrogen receptor signaling pathway. Effects of DHCA on RANKL-induced osteoclastogenesis were reduced when cells were treated with specific siRNA to ERα, but not to ERβ. Interestingly, DHCA was predicted from molecular docking simulation to bind to both ERα and ERβ. Indeed, data from an estrogen receptor competition assay revealed that DHCA acted as an agonist on both estrogen receptors. In the ovariectomized (Ovx) mouse model, DHCA prevented Ovx-induced bone loss by inhibiting osteoclastogenesis. Taken together, our results suggest that DHCA may be developed as an efficient therapeutic for osteoporosis by regulating osteoclastogenesis through its estrogenic effects.
Ovipositional Preferences of Two Squash Bug Species, Anasa tristis and Anasa armigera (Heteroptera: Coreidae), for Different Cultivars and Species of Cucurbitaceae.[Pubmed: 29718492]
The ovipositional preferences of two squash bug species, Anasa tristis (DeGeer) (Heteroptera: Coreidae) and Anasa armigera Say (Heteroptera: Coreidae), were evaluated in paired choice tests of different species and cultivars of plants in the family Cucurbitaceae. Females of A. tristis preferred to oviposit on the cultivar from which they were reared over three other cultivars of the same species. However, females did not show any ovipositional preference for different cultivars when they had no previous exposure to either cultivar. Females of A. tristis were equally likely to oviposit on Cucurbita pepo, Cucurbita maxima, and Cucurbita moschata but were significantly more likely to oviposit on C. pepo than on cucumber and watermelon. Females of A. armigera were equally likely to oviposit on C. pepo or cucumber, regardless of the species they were reared on. When A. armigera was reared on C. pepo, females were more likely to oviposit on C. maxima than on cucumber and less likely to oviposit on C. moschata than on cucumber.