Natural Products from Daphne tangutica
Natural Products Isolated from Daphne tangutica
BioCrick provides high-purity natural products and bioactive compounds isolated and purified from natural sources for scientific research.
- Natural product compounds selected from diverse chemical and biological sources.
- Broad structural diversity and coverage of biological activities.
- Product activity information can be supported by published literature, patents and research reports.
- Natural products can be selected according to source, target, activity and disease research interests.
- Compounds should be stored according to the product specifications after receipt.
Natural Products from Daphne tangutica
5 natural product s associated with Daphne tangutica
| Catalog No. | Product Name | CAS Number | COA |
|---|---|---|---|
| BCN1051 |
Daphnetin
|
486-35-1 | COA |
| BCN5488 |
Genkwanin
|
437-64-9 | COA |
| BCN4885 |
Hydroxygenkwanin
|
20243-59-8 | COA |
| BCN5581 |
Osthol
|
484-12-8 | COA |
| BCN4477 |
Umbelliferone
|
93-35-6 | COA |
References
Liquid chromatography with mass spectrometry and NMR spectroscopy based discovery of cytotoxic principles from Daphne tangutica Maxim.[Pubmed: 27062225]
An ethyl acetate extract from the barks of the ethnic Chinese medicine Daphne tangutica Maxim. exhibited antihepatocellular carcinoma activity against HepG2 and Hep3B cell lines. By using high-performance liquid chromatography based activity profiling in combination with offline liquid chromatography with mass spectrometry and NMR analysis, we rapidly identified ten major components of the extract, including seven active principles, coumarins (1-4) and biscoumarins (7, 8, 10), along with three inactive flavonoids (5, 6, 9). This study demonstrated that our combined protocol can be used as an important strategy for chemical profiling, dereplication as well as the identification of bioactive compounds from herbal medicines.
[Studies on the chemical constituents from Daphne tangutica].[Pubmed: 20432900]
To research the chemical constituents from Daphne tangutica.
Chemical constituents investigation of Daphne tangutica.[Pubmed: 19631260]
A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant.
Two new flavanes and bioactive compounds from Daphne tangutica Maxim.[Pubmed: 17691052]
Two new flavanes, named daphneflavan B (1) and daphneflavan C (2), along with two known biflavonoids, daphnodorin D(1) (3) and daphnodorin D(2) (4), were isolated from the roots of Daphne tangutica Maxim. Their structures were established on the basis of chemical, physicochemical, and spectroscopic evidences. Two compounds 3 and 4 were noted to have the most marked antitumor activity in vivo assay.
Antitumor activities of extracts and compounds from the roots of Daphne tangutica Maxim.[Pubmed: 17628482]
The antitumor activities of the crude extracts of Daphne tangutica Maxim. (Thymelaeaceae) and some compounds were investigated in vivo for the first time. The eight tested samples exhibited inhibition in mice transplanted with sarcoma S180. Of the eight samples, two samples DTE-2 (mixture of daphnodorin E and daphnodorin F) and DTE-3 (syringin) were noted to have the most marked antitumor activity.