Natural Products from Przewalskia tangutica
Natural Products Isolated from Przewalskia tangutica
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Natural Products from Przewalskia tangutica
6 natural product s associated with Przewalskia tangutica
References
Bioactive halogenated dihydroisocoumarins produced by the endophytic fungus Lachnum palmae isolated from Przewalskia tangutica.[Pubmed: 29421516]
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[Determination of tropane alkaloid components in Przewalskia tangutica Maxim. by capillary electrophoresis with electrochemiluminescence detection].[Pubmed: 18581856]
Based on an Eu-PB modified platinum electrode as the working electrode, a method for the simultaneous determination of the four tropane alkaloids, anisodamine, scopolamine, atropine and anisodine, by capillary electrophoresis with electrochemiluminescence detection (CE-ECL) has been established. The effects of several factors, such as the detection potential, the acidity and concentration of the running buffer, and the content of the methanol additive were investigated for the improvement of separation ability and detection sensitivity. Under the optimized conditions, these four components could be fully separated from each other in a 20 mmol/L phosphate (pH 8.0) containing 7% (v/v) methanol buffer within 6 min. The relative standard deviations of the peak area and migration time were less than 5.0% and 1.1% (n = 12) respectively for all the four compounds. Thus, the method has been successfully applied to the determination of anisodamine, scopolamine in Przewalskia tangutica Maxim. The average amounts of 27.8 g/kg anisodamine and 4.43 g/kg scopolamine were found in the herbal root-stalk sample. The recoveries of the tropane alkaloids were 97.8% - 102%.
Przewalskia tangutica - A tropane alkaloid-containing plant.[Pubmed: 17396796]
Przewalskia tangutica Maxim. (Solanaceae), a plant of Tibetan traditional medicine, was investigated. Contents of tropine, cuscohygrine, (-)-6beta-hydroxyhyoscyamine, hyoscyamine, apoatropine, scopolamine and daturamine were determined (Table I). The roots of this plant showed high contents of both hyoscyamine (major constituent) and total alkaloids, amounting to 1.67-3.82% and 2.06-4.01%, respectively. This plant and the crude drugs prepared from it are noteworthy as new sources of tropane alkaloids. The occurrence of tropane alkaloids in solanaceous plants of China is discussed briefly (Table II).