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cis-Vitisin B

CAS# 142507-86-6

cis-Vitisin B

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cis-Vitisin B: 5mg $1098 In Stock
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Chemical structure

cis-Vitisin B

Chemical Properties of cis-Vitisin B

Cas No. 142507-86-6 SDF Download SDF
PubChem ID N/A Appearance Yellow powder
Formula C56H42O12 M.Wt 906.9
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

cis-Vitisin B Dilution Calculator

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Preparing Stock Solutions of cis-Vitisin B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1027 mL 5.5133 mL 11.0266 mL 22.0531 mL 27.5664 mL
5 mM 0.2205 mL 1.1027 mL 2.2053 mL 4.4106 mL 5.5133 mL
10 mM 0.1103 mL 0.5513 mL 1.1027 mL 2.2053 mL 2.7566 mL
50 mM 0.0221 mL 0.1103 mL 0.2205 mL 0.4411 mL 0.5513 mL
100 mM 0.011 mL 0.0551 mL 0.1103 mL 0.2205 mL 0.2757 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on cis-Vitisin B

Anti-inflammatory effect of oligostilbenoids from Vitis heyneana in LPS-stimulated RAW 264.7 macrophages via suppressing the NF-kappaB activation.[Pubmed:29442202]

Chem Cent J. 2018 Feb 13;12(1):14.

BACKGROUND: Vitis heyneana is widely distributed in the north of Vietnam, it has been used in Vietnamese traditional medicine as an agent for treatment of arthritis, bronchitis, carbuncles and inflammatory conditions, and menstrual irregularities. However, this plant has not been investigated in phytochemical constituents and biological effects, especially in the anti-inflammatory property. RESULTS: Bioassay-guided fractionation of the EtOAc soluble fraction from the aerial part of Vitis heyneana resulted in the isolation of a series of oligostilbenoids as piceid (1), 2-r-viniferin (2), betulifol A (3), vitisinol C (4), (-)-trans-epsilon-viniferin (5), alpha-viniferin (6), shoreaketon (7), amurensin B (8), vitisinol B (9), and cis-Vitisin B (10). Compound 5 showed the most potent inhibitory activities by suppressing LPS-induced COX-2 expression and PGE2 production. This compound exhibited significantly reduced LPS-induced nitric oxide (NO) release in a dose-dependent manner. These effects are accompanied with the inhibition of transcription factor NF-kappaB activation. CONCLUSION: The results suggested that trans-epsilon-viniferin exerts anti-inflammatory effects via suppression the NF-kappaB activation in RAW 264.7 cells.

[Chemical constituents and cytotoxicity assay research in small polar substances from Vitis thunbergii var. taiwaniana].[Pubmed:26677700]

Zhongguo Zhong Yao Za Zhi. 2015 Aug;40(15):2999-3004.

This article studied the chemical constituents from the aerial part of Vitis thunbergii var. taiwaniana. The 60% ethanol extract was eluted with 95% ethanol though HP-20 macroporous adsorption resin column. 12 compounds, including (1) betulinic acid, (2)2, 2, 2'-bis (4-hydroxyphenyl) propane bis (2, 3-epoxypropyl) ether, (3) eriodictyol, (4) trans-epsilon-viniferin, (5) (+)-cis-epsilon-viniferin, (6) kobophenol A, (7) ampelopsin A, (8) nepalensinol B, (9) cis-miyabenol C, (10) cis-Vitisin B, (11) cis-gnetin H and (12) (+)-hopeaphenol, were separated by using normal phase silica gel, ODS, Sephdadex LH-20 column chromatographies and semi-preparative or preparative HPLC. Compounds 2, 5, 6, 8, 9, 10, 11 were separated from the genus Vitis for the first time and compounds 3, 7, 12 were separated from Vitis thunbergii var. taiwaniana for the first time. At a concentration of 50 mumol . L(-1), compound 6, 7 and 11 showed strong cytotoxicity against MCF-7 cell lines with the inhibition rate of 66.58%, 57.16%, 52.84%, respectively.

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