Blumeatin

Catalog No. BCN6055
CAS RN 118024-26-3
Molecular Weight 302.3
Molecular Formula C16H14O6
Database [PubChem]:382153844
[ChEBI]:
[PCIDB]:

Definition

Standard InChI

Biological Activity

Blumeatin was first isolated from Blumea balsamifera DC, it can inhibit the increase of serum alanine aminotransferase (AAT) and liver triglyceride and increased serum triglyceride, beta-lipoprotein, and liver glycogen content in CCl4-intoxicated rats, and can shorten the pentobarbital sleeping time in CCl4-intoxicated mice; suggestes that blumeatin can protect liver against injury induced by CCl4 and TAA.[1]
Blumeatin can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells, also enhances the accumulation of lipid droplets and induced upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4.[2]
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.[3,4]

Product information

English website: Blumeatin
Japanese website: Blumeatin
Chinese website: Blumeatin

References

[1] Xu S B, Chen W F, Liang H Q, et al. Acta Pharmacol Sin, 1993, 14(4):376-8.
[2] Zhang L B, Ji J, Lei C, et al. J Nat Prod, 2012, 75(4):699-706.
[3] Nessa F, Ismail Z, Mohamed N, et al. Food Chem, 2004, 88(2):243-52.
[4] Nessa F, Ismail Z, Mohamed N. Pharm Biol, 2010, 48(48):1405-12.
[5] Nessa F, Ismail Z, Karupiah S, et al. J Chromatogr Sci, 2005, 43(8):416-20.