A flavan-3,3',4',5,5',7-hexol having (2R,3R)-configuration.
InChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1
(-)-Epigallocatechin (EGC) can suppress oxidation of plasma low density lipoprotein (LDL) in vitro.[1]
Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cdelta and Nrf2.[2]
Cu(2+) with (-)-epigallocatechin (EGC) facilitated DNA cleavage, while Ag+ with EGC showed a strong repressive effect, the other metal ions examined showed little effect.[3]
English website: (-)-Epigallocatechin(EGC)
Japanese website: (-)-Epigallocatechin(EGC)
Chinese website: (-)-Epigallocatechin(EGC)
[1] Nakagawa K, Okuda S, Miyazawa T. Biosci Biotech Bioch, 1997, 61(12):1981-5.
[2] Ogborne R M, Rushworth S A, O Connell M A. Biochem Bioph Res Co, 2008, 373(4):584-8.
[3] Hayakawa F, Kimura T, Hoshino N, et al. Biosci Biotech Bioch, 1999, 63(9):1654-6.
[4] Deng YL, Feng L, Lu YC. Southwest China J Agr Sci, 2011, 24 (03): 932-5.
