Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN2804 | 7-O-Methylmangiferin |
| 7-O-Methylmangiferin is a natural product from Polygala tenuifolia. | |
| BCN4891 | 7-Oxo-beta-sitosterol |
| Standard reference | |
| BCN4194 | 7alpha-Hydroxystigmasterol |
| Standard reference | |
| BCN2751 | 7Beta-Hydroxycholesterol |
| 7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. 7beta-Hydroxycholesterol and 7-ketocholesterol have dual cytotoxic effects on the cells of the vascular wall by their ability to induce apoptosis in endothelial and smooth muscle cells and necrosis in fibroblasts. 7beta-Hydroxycholesterol can inhibit the proliferation of NCI-H460 cells through apoptosis via caspase activation. It can reinforce the susceptibility of K562 adriamycin-resistant cells to this drug, it also can enhance radiosensitivity in RDM4 cells. | |
| BCN1591 | 8,14-Epoxyergosta-4,22-diene-3,6-dione |
| (22E,24R)-8,14-epoxyergosta-4,22-diene-3,6-dione has antitumor activity, it may be disarming oncogenic pathways via direct modulation of the epigenetic machinery. | |
| BCN3117 | 8-Demethylsideroxylin |
| 8-Demethylsideroxylin is a natural product from Eucalyptus robusta Smith. | |
| BCN1443 | 8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen |
| Standard reference | |
| BCN3344 | 8-Methoxykaempferol |
| Standard reference | |
