Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6024 | Ganoderiol F |
| Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced HO-1 expression, activation of the mitogen-activated protein kinase EKR and up-regulation of cyclin-dependent kinase inhibitor p16 and suppressed lipopolysaccharide (LPS)-induced nitric oxide (NO) production. | |
| BCN6025 | Thevebioside |
| 1.Thevebioside and digitoxin are cardiac glycosides, have cardiac action. | |
| BCN6029 | Soyacerebroside II |
| 1. Soyacerebroside II exhibits ionophoretic activity for Ca2+ ion. 2. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral blood mononuclear cells (PBMC). | |
| BCN6032 | Dihydroniloticin |
| 1. Dihydroniloticin shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 8.2 microM). | |
| BCN6033 | Niloticin |
| 1. Niloticin can be used as a potential natural mosquitocide, it shows strong larvicidal and pupicidal activities, and shows good mosquitocidal activity against Ae. aegypti. 2. Niloticin can be used against the larvae of A. aegypti as an effective acetylcholinesterase (AChE) inhibitor. | |
| BCN6034 | Sootepin D |
| 1. Sootepin D shows anti-inflammatory activity. | |
| BCN6035 | Glaucin B |
| 1. Glacins A and B show potent and selective in vitro cytotoxicities among several human solid tumor cell lines. | |
| BCN6036 | 2'-Hydroxygenistein |
| 1. 2'-Hydroxygenistein has antifungal activity, dimerization of it causes a remarkable increase of antifungal activity. 2. 2'-Hydroxygenistein exhibits greater antiproliferative effects in MCF-7 human breast cancer cells than does genistein, suggest that 2'-hydroxylation of genistein can enhance its antioxidant activity and cell cytotoxicity in MCF-7 human breast cancer cells. 3. 2'-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils in response to formyl-Met-Leu-Phe/cytochalasin B. | |
