Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN6009 | 4-Allylpyrocatechol |
| 1. 4-Allylpyrocatechol has antioxidant activity. 2. 4-Allylpyrocatechol has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical and singlet oxygen scavenging properties. | |
| BCN6012 | 3-Deoxysappanone B |
| 1. 3-Deoxysappanone B has vasorelaxation effects, it can mediate endothelium- independent vasodilator action in rat thoracic aortic rings. | |
| BCN6013 | Magnoloside A |
| Magnoloside A has potent antifungal activities against various Cryptococcus strains with minimum inhibitory concentration values ranging from 1.0 to 4.0 ug/ml. | |
| BCN6014 | Stigmast-4-ene-3,6-diol |
| 1. Stigmast-4-ene-3beta,6beta-diol possesses marked inhibitory activity against 12-O- -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. | |
| BCN6015 | 3-(hydroxymethyl)cyclopentanone |
| 1. 3-Hydroxymethylcyclopentanone is a precursor to synthesize methyl epijasmonate. 2. 3-Hydroxymethylcyclopentanone compounds, which are useful as intermediates in the preparation of HIV chemokine CCR-5 receptor antagonists. | |
| BCN6019 | Caryophyllene oxide |
| Caryophyllene oxide, an oxygenated terpenoid existed in many plant essential oil, is well known as preservative in food, drugs and cosmetics with antifungal, acaricidal, anti-inflammatory, anti-carcinogenic, significant central as well as peripheral analgesic and skin penetration enhancing properties. Caryophyllene Oxide and lupenone have synergistic effect against Trypanosoma cruzi. It inhibited growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways, ROS-mediated MAPKs activation, and via modulation of 15-LOX. | |
| BCN6021 | 5-Hydroxy-7,8-dimethoxyflavanone |
| 1. 5-Hydroxy-7,8-dimethoxyflavanone shows anti-inflammatory activity, it can significantly decrease TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells. 2. (2S)-5-Hydroxy-7,8-dimethoxyflavanone is weakly active against human nasopharyngeal carcinoma cell line (KB) with IC50 value at 12.86 ug/ml. | |
| BCN6022 | Soyacerebroside I |
| 1. Soyacerebroside I demonstrates a potent tyrosinase inhibitory activity. 2. Soyacerebroside I shows anti-inflammatory activity, it can inhibit the accumulation of pro-inflammatory iNOS protein and reduce the expression of COX-2 protein in LPS-stimulated RAW264.7 macrophages. 3. Soyacerebrosides I and II have modulating the cellular immune response effects, they show obvious inhibitory activity on IL-18 secretion in human peripheral blood mononuclear cells (PBMC). | |
