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Aloe-emodin-8-O-beta-D-glucopyranoside

CAS# 33037-46-6

Aloe-emodin-8-O-beta-D-glucopyranoside

Catalog No. BCN1456----Order now to get a substantial discount!

Product Name & Size Price Stock
Aloe-emodin-8-O-beta-D-glucopyranoside: 5mg Please Inquire In Stock
Aloe-emodin-8-O-beta-D-glucopyranoside: 10mg Please Inquire In Stock
Aloe-emodin-8-O-beta-D-glucopyranoside: 20mg Please Inquire Please Inquire
Aloe-emodin-8-O-beta-D-glucopyranoside: 50mg Please Inquire Please Inquire
Aloe-emodin-8-O-beta-D-glucopyranoside: 100mg Please Inquire Please Inquire
Aloe-emodin-8-O-beta-D-glucopyranoside: 200mg Please Inquire Please Inquire
Aloe-emodin-8-O-beta-D-glucopyranoside: 500mg Please Inquire Please Inquire
Aloe-emodin-8-O-beta-D-glucopyranoside: 1000mg Please Inquire Please Inquire

Quality Control of Aloe-emodin-8-O-beta-D-glucopyranoside

Number of papers citing our products

Chemical structure

Aloe-emodin-8-O-beta-D-glucopyranoside

3D structure

Chemical Properties of Aloe-emodin-8-O-beta-D-glucopyranoside

Cas No. 33037-46-6 SDF Download SDF
PubChem ID 5317644 Appearance Yellow powder
Formula C21H20O10 M.Wt 432.4
Type of Compound Anthraquinones Storage Desiccate at -20°C
Synonyms 1-Hydroxy 3-hydroxymethylanthraquinone 8-glucoside
Solubility Soluble in methan
Chemical Name 1-hydroxy-3-(hydroxymethyl)-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
SMILES C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C=C(C=C4C2=O)CO)O
Standard InChIKey KIZBWUUJNJEYCM-JNHRPPPUSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Aloe-emodin-8-O-beta-D-glucopyranoside

1 Rheum sp.

Biological Activity of Aloe-emodin-8-O-beta-D-glucopyranoside

DescriptionAloe-emodin-8-O-beta-D-glucopyranoside shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
TargetsPTP1B
In vitro

PTP1B inhibitors from Saussrurea lappa.[Pubmed: 16864436 ]

J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.


METHODS AND RESULTS:
A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, Aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide.
CONCLUSIONS:
Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.

Aloe-emodin-8-O-beta-D-glucopyranoside Dilution Calculator

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Aloe-emodin-8-O-beta-D-glucopyranoside Molarity Calculator

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Preparing Stock Solutions of Aloe-emodin-8-O-beta-D-glucopyranoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3127 mL 11.5634 mL 23.1267 mL 46.2535 mL 57.8168 mL
5 mM 0.4625 mL 2.3127 mL 4.6253 mL 9.2507 mL 11.5634 mL
10 mM 0.2313 mL 1.1563 mL 2.3127 mL 4.6253 mL 5.7817 mL
50 mM 0.0463 mL 0.2313 mL 0.4625 mL 0.9251 mL 1.1563 mL
100 mM 0.0231 mL 0.1156 mL 0.2313 mL 0.4625 mL 0.5782 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Aloe-emodin-8-O-beta-D-glucopyranoside

PTP1B inhibitors from Saussrurea lappa.[Pubmed:16864436]

J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.

A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, Aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide. Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.

Description

Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM.

Keywords:

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