Sennoside D

CAS# 37271-17-3

Sennoside D

Catalog No. BCN1005----Order now to get a substantial discount!

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Sennoside D: 5mg $81 In Stock
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Quality Control of Sennoside D

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Chemical structure

Sennoside D

3D structure

Chemical Properties of Sennoside D

Cas No. 37271-17-3 SDF Download SDF
PubChem ID 46173830 Appearance Yellow powder
Formula C42H40O19 M.Wt 848.76
Type of Compound Anthraquinones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (9R)-4-hydroxy-9-[(9S)-4-hydroxy-2-(hydroxymethyl)-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
SMILES C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C=C(C=C4C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)CO)O
Standard InChIKey ZFWOUNNKSHIAFK-MIIKWYNKSA-N
Standard InChI InChI=1S/C42H40O19/c43-11-14-7-18-26(16-3-1-5-22(30(16)34(50)28(18)20(46)8-14)58-41-38(54)36(52)32(48)24(12-44)60-41)27-17-4-2-6-23(59-42-39(55)37(53)33(49)25(13-45)61-42)31(17)35(51)29-19(27)9-15(40(56)57)10-21(29)47/h1-10,24-27,32-33,36-39,41-49,52-55H,11-13H2,(H,56,57)/t24-,25-,26+,27-,32-,33-,36+,37+,38-,39-,41-,42-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Sennoside D

The leaves of Cassia angustifolia.

Biological Activity of Sennoside D

DescriptionSennoside D is a natural product from Cassia angustifolia.

Protocol of Sennoside D

Structure Identification
Chinese Journal of Experimental Traditional Medical Formulae,2012 ,18 (6) :10-12.

Stability of Active Ingredients from Rheum officinale in Concentration and Drying Process.[Reference: WebLink]

To study on stability of active ingredients from Rheum officinale in concentration and drying process.
METHODS AND RESULTS:
Taking active ingredients from extraction fluid of R.officinale as studying target,samples were taken at different time points in concentration and drying progress,change trends of relative content was determined by HPLC. The relative content of active ingredients were degraded greater degree after concentrated 1 h in process of heating at 70 ℃,its reduction is not obvious after concentrated 2 h by comparing with 1 h,but after concentrated for 3 h,the relative content reduced significantly;At 70 ℃ vacuum drying process,active ingredients were in large degree of degradation after drying 2 h,the change of content was small after drying 3 h by comparing with 2 h,general trend was relative stable,the content of active ingredients was less affected in drying process.Sennoside D decomposed easily in heating.
CONCLUSIONS:
During in process of concentration and drying at 70 ℃ vacuum for extraction fluid from R.officinale,concentration time should be controlled within 2 h,components were stable in drying time for 3 h.

Sennoside D Dilution Calculator

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Sennoside D Molarity Calculator

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Preparing Stock Solutions of Sennoside D

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1782 mL 5.8909 mL 11.7819 mL 23.5638 mL 29.4547 mL
5 mM 0.2356 mL 1.1782 mL 2.3564 mL 4.7128 mL 5.8909 mL
10 mM 0.1178 mL 0.5891 mL 1.1782 mL 2.3564 mL 2.9455 mL
50 mM 0.0236 mL 0.1178 mL 0.2356 mL 0.4713 mL 0.5891 mL
100 mM 0.0118 mL 0.0589 mL 0.1178 mL 0.2356 mL 0.2945 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Sennoside D

Stability of Active Ingredients from Rheum officinale in Concentration and Drying Process.

Chinese Journal of Experimental Traditional Medical Formulae,2012 ,18 (6) :10-12.

To study on stability of active ingredients from Rheum officinale in concentration and drying process.Method:Taking active ingredients from extraction fluid of R.officinale as studying target,samples were taken at different time points in concentration and drying progress,change trends of relative content was determined by HPLC.Result:The relative content of active ingredients were degraded greater degree after concentrated 1 h in process of heating at 70 ℃,its reduction is not obvious after concentrated 2 h by comparing with 1 h,but after concentrated for 3 h,the relative content reduced significantly;At 70 ℃ vacuum drying process,active ingredients were in large degree of degradation after drying 2 h,the change of content was small after drying 3 h by comparing with 2 h,general trend was relative stable,the content of active ingredients was less affected in drying process.Sennoside D decomposed easily in heating.Conclusion:During in process of concentration and drying at 70 ℃ vacuum for extraction fluid from R.officinale,concentration time should be controlled within 2 h,components were stable in drying time for 3 h.

Description

Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).

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