Citromycin

CAS# 37209-30-6

Citromycin

2D Structure

Catalog No. BCN7459----Order now to get a substantial discount!

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3D structure

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Citromycin

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Chemical Properties of Citromycin

Cas No. 37209-30-6 SDF Download SDF
PubChem ID 3084655 Appearance Powder
Formula C13H10O5 M.Wt 246.21
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 8,9-dihydroxy-2-methyl-5H-pyrano[3,2-c]chromen-4-one
SMILES CC1=CC(=O)C2=C(O1)C3=CC(=C(C=C3OC2)O)O
Standard InChIKey QZZUHPUWIRSQPB-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H10O5/c1-6-2-9(14)8-5-17-12-4-11(16)10(15)3-7(12)13(8)18-6/h2-4,15-16H,5H2,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Citromycin

The cultures of two strains of Streptomyces.

Biological Activity of Citromycin

Description1. Citromycin, an antibiotic, has weakly cytotoxic.
TargetsAntifection

Citromycin Dilution Calculator

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Citromycin Molarity Calculator

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Preparing Stock Solutions of Citromycin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0616 mL 20.3079 mL 40.6157 mL 81.2315 mL 101.5393 mL
5 mM 0.8123 mL 4.0616 mL 8.1231 mL 16.2463 mL 20.3079 mL
10 mM 0.4062 mL 2.0308 mL 4.0616 mL 8.1231 mL 10.1539 mL
50 mM 0.0812 mL 0.4062 mL 0.8123 mL 1.6246 mL 2.0308 mL
100 mM 0.0406 mL 0.2031 mL 0.4062 mL 0.8123 mL 1.0154 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Citromycin

Citromycetins and bilains A-C: new aromatic polyketides and diketopiperazines from Australian marine-derived and terrestrial Penicillium spp.[Pubmed:17958395]

J Nat Prod. 2007 Nov;70(11):1746-52.

Chemical analysis of an Australian marine-derived isolate of Penicillium bilaii, collected from the Huon estuary, Port Huon, Tasmania, yielded the known fungal aromatic polyketides citromycetin (1) and Citromycin (2) together with two dihydro analogues, (-)-2,3-dihydrocitromycetin (3) and (-)-2,3-dihydroCitromycin (4). An Australian terrestrial isolate of Penicillium striatisporum collected near Shalvey, New South Wales, also yielded citromycetin (1), Citromycin (2), and the new dihydro analogue (-)-2,3-dihydrocitromycetin (3), together with fulvic acid (5), anhydrofulvic acid (6), and a selection of new methoxylated analogues, 12-methoxycitromycetin (7), 12-methoxyCitromycin (8), (-)-12-methoxy-2,3-dihydrocitromycetin (9), and 12-methoxyanhydrofulvic acid (10). P. bilaii also yielded the rare siderophore pistillarin (11), the known diketopiperazines cyclo-(L-Phe -L-Pro) (12), cyclo-(L-Pro-L-Tyr) (13), cyclo-(L-Pro-L-Val) (14), and cis-bis(methylthio)silvatin (15), and three new diketopiperazines, bilains A-C (16-18). The structures for the Penicillium metabolites 1- 18 were assigned by a combination of detailed spectroscopic analysis, including correlation with relevant literature data, chemical derivatization, degradation, and biosynthetic considerations. The Citromycin polyketides 2 and 4 and the diketopiperazine 15 were weakly cytotoxic.

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