3,4-Secocucurbita-4,24-diene-3,26,29-trioic acidCAS# 329975-47-5 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 329975-47-5 | SDF | Download SDF |
| PubChem ID | 101095218 | Appearance | Powder |
| Formula | C30H46O6 | M.Wt | 502.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (E,6R)-6-[(3R,3aR,5aS,6S,7E,9aR,9bS)-6-(2-carboxyethyl)-7-(1-carboxyethylidene)-3a,5a,9b-trimethyl-2,3,4,5,6,8,9,9a-octahydro-1H-cyclopenta[a]naphthalen-3-yl]-2-methylhept-2-enoic acid | ||
| SMILES | CC(CCC=C(C)C(=O)O)C1CCC2(C1(CCC3(C2CCC(=C(C)C(=O)O)C3CCC(=O)O)C)C)C | ||
| Standard InChIKey | MLKGNOBMWJPGDM-HKQAYJIZSA-N | ||
| Standard InChI | InChI=1S/C30H46O6/c1-18(8-7-9-19(2)26(33)34)22-14-15-30(6)24-12-10-21(20(3)27(35)36)23(11-13-25(31)32)28(24,4)16-17-29(22,30)5/h9,18,22-24H,7-8,10-17H2,1-6H3,(H,31,32)(H,33,34)(H,35,36)/b19-9+,21-20+/t18-,22-,23-,24-,28+,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Russula lepida
| Description | 1. (24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM. |
3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid Dilution Calculator
3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9893 mL | 9.9463 mL | 19.8926 mL | 39.7852 mL | 49.7315 mL |
| 5 mM | 0.3979 mL | 1.9893 mL | 3.9785 mL | 7.957 mL | 9.9463 mL |
| 10 mM | 0.1989 mL | 0.9946 mL | 1.9893 mL | 3.9785 mL | 4.9731 mL |
| 50 mM | 0.0398 mL | 0.1989 mL | 0.3979 mL | 0.7957 mL | 0.9946 mL |
| 100 mM | 0.0199 mL | 0.0995 mL | 0.1989 mL | 0.3979 mL | 0.4973 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- TTP 22
Catalog No.:BCC2017
CAS No.:329907-28-0
- Viomycin
Catalog No.:BCC3930
CAS No.:32988-50-4
- Tobramycin
Catalog No.:BCC4739
CAS No.:32986-56-4
- 10-Deacetylbaccatin III
Catalog No.:BCN5251
CAS No.:32981-86-5
- Methyl (2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate
Catalog No.:BCN8520
CAS No.:32981-85-4
- Cinaciguat
Catalog No.:BCC1484
CAS No.:329773-35-5
- 2-Acetyl-3-ethylpyrazine
Catalog No.:BCC8512
CAS No.:32974-92-8
- Pinoresinol diacetate
Catalog No.:BCN5250
CAS No.:32971-25-8
- FPR A14
Catalog No.:BCC7498
CAS No.:329691-12-5
- 7-O-Methylaloeresin A
Catalog No.:BCN2849
CAS No.:329361-25-3
- Sanggenol L
Catalog No.:BCN3692
CAS No.:329319-20-2
- Boc-His(Trt)-OH
Catalog No.:BCC3403
CAS No.:32926-43-5
New Products
- Nicarbazin
Catalog No.:BCC9101
CAS No.:330-95-0
- Kumatakenin
Catalog No.:BCN5252
CAS No.:3301-49-3
- ent-16beta,17-Dihydroxy-19-kauranoic acid
Catalog No.:BCN1457
CAS No.:3301-61-9
- Cyanidin-3-O-sambubioside chloride
Catalog No.:BCN3150
CAS No.:33012-73-6
- SU6656
Catalog No.:BCC6392
CAS No.:330161-87-0
- TC HSD 21
Catalog No.:BCC6228
CAS No.:330203-01-5
- Boc-β-Ala-OH
Catalog No.:BCC3051
CAS No.:3303-84-2
- Aloe-emodin-8-O-beta-D-glucopyranoside
Catalog No.:BCN1456
CAS No.:33037-46-6
- H-Orn(Z)-OH
Catalog No.:BCC3003
CAS No.:3304-51-6
- Peramivir
Catalog No.:BCC1846
CAS No.:330600-85-6
- TCTU
Catalog No.:BCC2689
CAS No.:330641-16-2
- HCTU
Catalog No.:BCC2818
CAS No.:330645-87-9
Structures and biological activities of triterpenes and sesquiterpenes obtained from Russula lepida.[Pubmed:27066716]
Phytochemistry. 2016 Jul;127:63-8.
A seco-cucurbitane triterpene and two aristolane sesquiterpenes, named (24E)-3,4-seco-cucurbita-4,24-diene-3-hydroxy-26,29-dioic acid, (+)-1,2-didehydro-9-hydroxy-aristlone, and (+)-12-hydroxy-aristlone, were isolated from fruiting bodies of the medicinal mushroom Russula lepida, together with (24E)-3,4-seco-cucurbita-4,24-diene-3,26,29-trioic acid and (+)-aristlone. The structures of the first three compounds, including their absolute configurations, were assigned on the basis of their NMR and ECD spectra. Two seco-cucurbitane triterpenes, (24E)-3,4-seco-cucurbita-4,24-diene-3-hydroxy-26,29-dioic acid and (24E)-3,4-seco-cucurbita-4,24-diene-3,26,29-trioic acid, inhibited the activity of protein tyrosine phosphatase 1B (PTP1B), with IC50 values of 20.3 and 0.4muM, respectively. All isolated compounds did not show cytotoxicity against human cancer cell lines, Huh-7 (hepatoma) and EJ-1 (bladder), at 50muM.
3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid,329975-47-5,Natural Products, buy 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid , 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid supplier , purchase 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid , 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid cost , 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid manufacturer , order 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid , high purity 3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid
