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TCTU

CAS# 330641-16-2

TCTU

2D Structure

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3D structure

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TCTU

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Chemical Properties of TCTU

Cas No. 330641-16-2 SDF Download SDF
PubChem ID 24898642 Appearance Powder
Formula C11H15BClF4N5O M.Wt 355.53
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(6-chlorobenzotriazol-1-yl)oxy-(dimethylamino)methylidene]-dimethylazanium;tetrafluoroborate
SMILES [B-](F)(F)(F)F.CN(C)C(=[N+](C)C)ON1C2=C(C=CC(=C2)Cl)N=N1
Standard InChIKey GBGVQFJZGHBZMC-UHFFFAOYSA-N
Standard InChI InChI=1S/C11H15ClN5O.BF4/c1-15(2)11(16(3)4)18-17-10-7-8(12)5-6-9(10)13-14-17;2-1(3,4)5/h5-7H,1-4H3;/q+1;-1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

TCTU Dilution Calculator

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TCTU Molarity Calculator

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Preparing Stock Solutions of TCTU

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8127 mL 14.0635 mL 28.127 mL 56.254 mL 70.3176 mL
5 mM 0.5625 mL 2.8127 mL 5.6254 mL 11.2508 mL 14.0635 mL
10 mM 0.2813 mL 1.4064 mL 2.8127 mL 5.6254 mL 7.0318 mL
50 mM 0.0563 mL 0.2813 mL 0.5625 mL 1.1251 mL 1.4064 mL
100 mM 0.0281 mL 0.1406 mL 0.2813 mL 0.5625 mL 0.7032 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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TCTU

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References on TCTU

TcTU before and after exogeneous TSH suppression in diagnosing thyroid autonomy.[Pubmed:2167603]

Acta Med Austriaca. 1990;17 Suppl 1:54-5.

In 104 euthyroid patients with goiter and suspected thyroid autonomy two thyroid scintiscans with quantification of the TCTU were performed before (TCTUo) and after exogeneous TSH suppression (TCTUs). In 15 patients with subnormal TSH before suppression the TCTUs revealed no difference to the TCTUo. In contrast to the TCTUo, in euthyroid patients the TCTUs is not relevantly influenced by individual iodine supply. In euthyroid goitreous patients with normal TSH a TCTUo less than 2.0% resulted in a TCTUs less than 1.1% in all 22 cases and, therefore, in these patients a scintiscan after TSH suppression is not necessary, because no relevant mass of functional autonomous tissue can be expected. In all other patients with normal TSH only the TCTUs is relevant for identification of thyroid autonomy. Autonomy with a TCTUs greater than 1.5% and, consequently, with a suspected higher risk of hyperthyroidism after iodine contamination was found in 19% (17/89) of the goitreous patients with normal TSH.

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