Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN1535 | 9-O-Feruloyl-5,5'-dimethoxylariciresinol |
| 1. (+)-9'-O-trans-Feruloyl-5,5'-dimethoxylariciresinol shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml. 2. (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol can inhibit release of histamine from mast cells, it may have anti-allergic inflammatory effect. | |
| BCN1191 | Pedunculoside |
| Pedunculoside shows significant hypocholesterolemic and anti-inflammatory activities, it shows potential nitric oxide inhibitory activities with the IC50 value ranging from 14.92 uM to 52.23 uM. | |
| BCN1192 | Zingerone |
| Zingerone has anti-mutagenic, anti-carcinogenic, anti-obesity,anti-oxidative and anti-inflammatory activities. Zingerone can be recommended as a supplement to shrimp feed to increase growth, immunity, and disease resistance against the pathogen, V.alginolyticus , use of zingerone as appetizer and immunostimulant in shrimp is promising. It could as potential phytotherapeutic agent which in future can be employed to formulate preventive strategies against biofilm associated infections caused by P.aeruginosa. | |
| BCN1193 | alpha-Cyperone |
| Alpha-cyperone is associated with the down-regulation of COX-2,IL-6,Nck-2,Cdc42 and Rac1, resulting in reduction of inflammation. which would be highly beneficial for treatment of inflammatory diseases such as AD. Alpha-cyperone is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium, it also shows inhibitory effects on adherence and invasion of avian pathogenic Escherichia coli O78 to chicken type II pneumocytes. | |
| BCN1194 | Sanggenone D |
| 1. Sanggenones D, B, O,G show an antifungal activity with IC50 values between 10 and 123 microM. 2. Sanggenones(sanggenones C, D) represent a new scaffold of positive GABAA receptor modulators. 3. Sanggenones D, C and kazinol B inhibit COX-2 activity (ic 50 = 73-100 μM). 4. Sanggenone D has anti-inflammatory activity, it can inhibit NO production from lipopolysaccharide (LPS)-induced RAW 264.7 cells at > 10 uM; inhibition of nitric oxide production was mediated by suppression of iNOS enzyme induction but not by direct inhibition of iNOS enzyme activity. | |
| BCN1195 | Forsythoside A |
| Forsythoside A possesses strong antibacterial, antiinflammatory, antioxidant and antiviral effects. it has the potential to prevent IBV infection in vitro, it can promote the expression of IFN-α and Mx1 significantly.Forsythoside A has inductive effects on the activities of CYP1A2 and CYP2C11, without affecting CYP2D1 and CYP3A1/2 activities. | |
| BCN1196 | 5,15-Diacetyl-3-benzoyllathyrol |
| 5,15-Diacetyl-3-benzoyllathyrol is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability. | |
| BCN1197 | Levistilide A |
| Traditional formula compatibility of Danggui-Shaoyao-San could significantly enhance levistilide A bioavailability compared with levistilide A alone and Rhizoma Chuanxiong. Senkyunolide O is a COX-2 selective inhibitor with the IC(50) value of 5 microM. | |
