5,15-Diacetyl-3-benzoyllathyrolCAS# 218916-52-0 |
Quality Control & MSDS
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| Cas No. | 218916-52-0 | SDF | Download SDF |
| PubChem ID | 10577938 | Appearance | Powder |
| Formula | C31H38O7 | M.Wt | 522.63 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Synonyms | Euphorbia factor L3 | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(1R,3E,5R,7S,11R,12R,13S,14S)-1,11-diacetyloxy-3,6,6,14-tetramethyl-10-methylidene-2-oxo-13-tricyclo[10.3.0.05,7]pentadec-3-enyl] benzoate | ||
| SMILES | CC1CC2(C(C1OC(=O)C3=CC=CC=C3)C(C(=C)CCC4C(C4(C)C)C=C(C2=O)C)OC(=O)C)OC(=O)C | ||
| Standard InChIKey | JPYYWXPAHJBKJX-VWSFRBHVSA-N | ||
| Standard InChI | InChI=1S/C31H38O7/c1-17-13-14-23-24(30(23,6)7)15-18(2)28(34)31(38-21(5)33)16-19(3)27(25(31)26(17)36-20(4)32)37-29(35)22-11-9-8-10-12-22/h8-12,15,19,23-27H,1,13-14,16H2,2-7H3/b18-15+/t19-,23-,24+,25-,26-,27-,31+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The seeds of Euphorbia lathyris L.
| Description | 5,15-Diacetyl-3-benzoyllathyrol is a melanine production inhibitor, excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles, has excellent stability. |
| In vitro | Skin whitener[Reference: WebLink]US6838481[P]. 2005.The invention relates to 5,15-Diacetyl-3-benzoyllathyrol compound and a skin whitening composition containing the same. Since the composition of the invention contains 5,15-Diacetyl-3-benzoyllathyrol as a melanine production inhibitor, it is excellent in inhibiting pigment stagnation and improving the discoloration of the skin or freckles. In addition, since it does not induce a secondary effect, it has excellent stability. |
5,15-Diacetyl-3-benzoyllathyrol Dilution Calculator
5,15-Diacetyl-3-benzoyllathyrol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9134 mL | 9.567 mL | 19.134 mL | 38.268 mL | 47.835 mL |
| 5 mM | 0.3827 mL | 1.9134 mL | 3.8268 mL | 7.6536 mL | 9.567 mL |
| 10 mM | 0.1913 mL | 0.9567 mL | 1.9134 mL | 3.8268 mL | 4.7835 mL |
| 50 mM | 0.0383 mL | 0.1913 mL | 0.3827 mL | 0.7654 mL | 0.9567 mL |
| 100 mM | 0.0191 mL | 0.0957 mL | 0.1913 mL | 0.3827 mL | 0.4783 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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5,15-Diacetyl-3-benzoyllathyrol is one of the lathyrane diterpenoids, that has anti-cancer activity.
In Vitro:5,15-Diacetyl-3-benzoyllathyrol shows anticancer activity in vitro against lung cancer A549 cells and the IC50 values are 34.04±3.99 μM. Furthermore, 5,15-Diacetyl-3-benzoyllathyrol can induce apoptosis in A549 cells via the mitochondrial pathway including loss of mitochondrial potential and release of cytochrome c[1].
References:
[1]. Zhang JY, et al. Structure identification of Euphorbia factor L3 and its induction of apoptosis through the mitochondrial pathway. Molecules. 2011 Apr 15;16(4):3222-31.
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5,15-Diacetyl-3-benzoyllathyrol is one of the lathyrane diterpenoids, that has anti-cancer activity.
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