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Euphorbia factor L9

CAS# 129393-28-8

Euphorbia factor L9

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Quality Control of Euphorbia factor L9

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Chemical structure

Euphorbia factor L9

3D structure

Chemical Properties of Euphorbia factor L9

Cas No. 129393-28-8 SDF Download SDF
PubChem ID 102004672 Appearance Powder
Formula C37H41NO9 M.Wt 643.7
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1CC2(C(C1OC(=O)C3=CC=CC=C3)C(C(=C)C(CC4C(C4(C)C)C=C(C2=O)C)OC(=O)C5=CN=CC=C5)OC(=O)C)OC(=O)C
Standard InChIKey KJVZJVTXTSJYTG-DHTCIELZSA-N
Standard InChI InChI=1S/C37H41NO9/c1-20-16-27-28(36(27,6)7)17-29(45-35(43)26-14-11-15-38-19-26)22(3)32(44-23(4)39)30-31(46-34(42)25-12-9-8-10-13-25)21(2)18-37(30,33(20)41)47-24(5)40/h8-16,19,21,27-32H,3,17-18H2,1-2,4-7H3/b20-16-/t21-,27+,28-,29+,30+,31-,32-,37+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Euphorbia factor L9

The herbs of Euphorbia pekinensis Rupr.

Protocol of Euphorbia factor L9

Structure Identification
Phytochemical Analysis, 2001, 12(4):255–262.

HPLC‐UV and HPLC‐positive‐ESI‐MS analysis of the diterpenoid fraction from caper spurge  (Euphorbia lathyris) seed oil.[Reference: WebLink]


METHODS AND RESULTS:
Caper spurge (Euphorbia lathyris L.) seed oil contains a series of diterpenoids known as Euphorbia factors, or L‐factors, L1–L9(Euphorbia factor L1,Euphorbia factor L2, Euphorbia factor L3, Euphorbia factor L4 ,Euphorbia factor L5, Euphorbia factor L6, Euphorbia factor L7, Euphorbia factor L8, Euphorbia factor L9 ). They are esters of several polyols (lathyrol, epoxylathyrol, hydroxylathyrol and ingenol) and account for about 3–5% of the oil. The percentage of ingenol‐based L‐factors is very low, less than 5% of the diterpenoid fraction, but some of them (factors L5 and L6) are responsible for the irritant and co‐carcinogenic activities of the oil.
CONCLUSIONS:
This paper reports an HPLC‐UV and HPLC‐positive‐ESI‐MS analysis of the diterpenoid fraction of caper spurge seed oil before and after selective hydrolysis of ingenol‐based L‐factors. Separation of lathyrane polyols and esters, and ingenol and its esters was achieved using a chromatographic system consisting of a C18 stationary phase and acetonitrile:water as mobile phase. A new macrocyclic constituent, the deoxy Euphorbia factor L1, was identified in the oil.

Euphorbia factor L9 Dilution Calculator

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Preparing Stock Solutions of Euphorbia factor L9

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5535 mL 7.7676 mL 15.5352 mL 31.0704 mL 38.838 mL
5 mM 0.3107 mL 1.5535 mL 3.107 mL 6.2141 mL 7.7676 mL
10 mM 0.1554 mL 0.7768 mL 1.5535 mL 3.107 mL 3.8838 mL
50 mM 0.0311 mL 0.1554 mL 0.3107 mL 0.6214 mL 0.7768 mL
100 mM 0.0155 mL 0.0777 mL 0.1554 mL 0.3107 mL 0.3884 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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