BoscialinCAS# 129277-03-8 |
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| Cas No. | 129277-03-8 | SDF | Download SDF |
| PubChem ID | 6442487 | Appearance | Powder |
| Formula | C13H22O3 | M.Wt | 226.31 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (E)-4-[(1S,4S,6R)-1,4-dihydroxy-2,2,6-trimethylcyclohexyl]but-3-en-2-one | ||
| SMILES | CC1CC(CC(C1(C=CC(=O)C)O)(C)C)O | ||
| Standard InChIKey | CWLKAPCFJXJCEO-SGEPYOGPSA-N | ||
| Standard InChI | InChI=1S/C13H22O3/c1-9-7-11(15)8-12(3,4)13(9,16)6-5-10(2)14/h5-6,9,11,15-16H,7-8H2,1-4H3/b6-5+/t9-,11+,13-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The leaves of Tripterygium wilfordii Hook.f.
| Description | 1. Boscialin can inhibit signal transducer and activator of transcription 1 translocation at a concentration of 10 uM. |
Boscialin Dilution Calculator
Boscialin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.4187 mL | 22.0936 mL | 44.1872 mL | 88.3744 mL | 110.4679 mL |
| 5 mM | 0.8837 mL | 4.4187 mL | 8.8374 mL | 17.6749 mL | 22.0936 mL |
| 10 mM | 0.4419 mL | 2.2094 mL | 4.4187 mL | 8.8374 mL | 11.0468 mL |
| 50 mM | 0.0884 mL | 0.4419 mL | 0.8837 mL | 1.7675 mL | 2.2094 mL |
| 100 mM | 0.0442 mL | 0.2209 mL | 0.4419 mL | 0.8837 mL | 1.1047 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Wilfordonols A-D: four new norsesquiterpenes from the leaves of Tripterygium wilfordii.[Pubmed:26096035]
J Asian Nat Prod Res. 2015;17(6):615-24.
Four new norsesquiterpenes wilfordonols A-D (1-4), along with three known compounds, sarmentol B (5), Boscialin (6), and (+)-loliolide (7), were isolated from the leaves of Tripterygium wilfordii Hook.f.. The structures of the new compounds were elucidated on the basis of their spectroscopic analysis, and the absolute configuration of the compounds was confirmed by CD and modified Mosher's method. At a concentration of 10 muM, compounds 4, 6, and 7 inhibited signal transducer and activator of transcription 1 translocation by 34.27 +/- 1.02%, 48.93 +/- 1.76%, and 70.31 +/- 2.20%, respectively.
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