Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 5145 - 5152 of 9359 hot products
| Catalog No. | Product Name |
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| BCN3170 | Mogroside III-A1 |
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Mogroside III-A1 is a natural product from Siraitia grosvenorii Swingle.
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| BCN3171 | 3-oxo-Olean-12-en-28-oic acid |
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3-oxo-Olean-12-en-28-oic acid and kulinone have cytotoxic effects, with IC50 values of 5.6-21.2 μg/mL.
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| BCN3172 | Polygalic acid |
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Polygalic acid, a triterpenoid saponin, shows expectorant, emetic and stimulant effects.
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| BCN3173 | 3-Epiursolic acid |
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1. 3-Epiursolic acid shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 uM, cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents.
2. 3-Epiursolic acid may have antiinflammatory activity. |
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| BCN3174 | Mahanimbine |
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1. Mahanimbine inhibits AChE activity in a dose-dependent manner.
2. Mahanimbine and mangiferin increases the glucose utilization in a dose-dependent manner, can prevent obesity and use in management of diabetes. 3. Mahanimbine can prevent high-fat diet (HFD)-induced hyperlipidemia and fat accumulation in adipose tissue and liver along with the restricted progression of systemic inflammation and oxidative stress. 4. Mahanimbine can lower the absorption of dietary fat resulting in dietary fat excretion. |
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| BCN3175 | Isomahanimbine |
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1. Isomahanimbine shows protection in liver.
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| BCN3176 | Mahanine |
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1. Mahanine has a dose- and time-dependent anti-proliferative activity in acute lymphoid (MOLT-3) and chronic myeloid (K562) leukemic cell lines.
2. Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. 3. Mahanine can reverse an epigenetically silenced gene, RASSF1A in prostate cancer cells by inhibiting DNMT activity that in turn down-regulates a key cell cycle regulator, cyclin D1, is an encouraging therapeutic choice for advanced prostatic cancer. 4. Mahanine inhibited growth of PC3 and LNCaP prostate cancer cells in a dose and time-dependent manner, inhibits growth and induces apoptosis in both androgen-responsive, LNCaP and androgen-independent, PC3 cells by targeting cell survival pathway. |
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| BCN3177 | Isomahanine |
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1. Isomahanine and mahanine show antibacterial activity towards Flavobacterium columnare and Streptococcus iniae which caused columnaris disease and streptococcosis respectively; isomahanine has the strongest activity against F. columnare (isolate ALM-00-173) and S. iniae (isolate LA94-426) based on 24-h 50% inhibition concentration (IC50) and minimum inhibition concentration (MIC).
2. Isomahanine is a potent inhibitor of sEH , with IC50 values of 22.565±651.7. |
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