Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 6065 - 6072 of 9359 hot products
| Catalog No. | Product Name |
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| BCN4315 | Quassin |
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1. Quassin exhibits P. falciparum inhibitory activity (IC50=0.06 micro g/ml, 0.15 micro M).
2. Quassin can significantly increase red blood cell count, pack cell volume and haemoglobin concentration, suggests that it possesses anti-anaemic property. 3. Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion. 4. Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. |
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| BCN4317 | Mallorepine |
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1. Mallorepine may propably be an intermediate on the biosynthetic pathway from nicotinamide (II) to ricinine (III).
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| BCN4318 | Camptothecin |
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Camptothecin is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM; it is a novel alkaloidal leukemia and tumor inhibitor, is a strong inhibitor of nucleic acid synthesis in mammalian cells and a potent inducer of strand breaks in chromosomal DNA. Camptothecin and its analogs reduce amyloid-β production and amyloid-β42-induced IL-1β production.
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| BCN4320 | Cleomiscosin A |
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1. Cleomiscosin A and brusatol are antitumor agents, have antileukemic principles.
2. Cleomiscosin A has antioxidant activity, it could be beneficial in preventing LDL oxidation in atherosclerotic lesions. 3. Cleomiscosin A methyl ether derivatives have anti-inflammatory activity. 4. Cleomiscosin A shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. 5. The mixture of three compounds (cleomiscosin A, B and C) is showing the significant protective effects against CCl(4)-induced hepatotoxicity in small animals and also coumarinolignoids are well tolerated by small animals in acute oral study. |
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| BCN4321 | 15-Methoxypinusolidic acid |
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1. 15-Methoxypinusolidic acid induced apoptosis in murine microglial cells, presumably via inhibition of the cell cycle progression.
2. 15-Methoxypinusolidic acid inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB, suggesting a potential anti-inflammatory effect of the compound on microglial cells. 3. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dependent adipogenic gene expression. 4. 15-Methoxypinusolidic acid attenuates glutamate-induced excitotoxicity via stabilization of [Ca2+]i homeostasis and suppression of oxidative stress possibly through the actions on the NMDA receptors. |
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| BCN4322 | Garcinone C |
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1. Garcinone C is the most potent inhibitor of AChE.
2. Garcinone C is the most active compound against both of pathogenic (MIC =100 μg/ml) and non-pathogenic leptospira (MIC = 200 μg/ml). 3. Garcinone C exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines in vitro. |
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| BCN4324 | 1H-Indole-3-carboxylic acid |
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Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite which belongs to a class of organic compounds known as indolecarboxylic acids and derivatives.
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| BCN4325 | Drimiopsin C |
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Drimiopsin C is a natural product from Scilla scilloides.
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