Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC3578 | Sulfo-NHS-LC-Biotin |
| Sulfo-NHS-LC-Biotin is an intermediate length, water-soluble biotinyltation reagent used to attach biotin to primary amines. | |
| BCC3579 | NHS-LC-Biotin |
| NHS-LC-Biotin is a amine-reactive biotinylation agent | |
| BCC3580 | Sulfo-NHS-SS-Biotin |
| Sulfo-NHS-SS-Biotin is a water-soluble, NHS-ester biotinylation reagent | |
| BCC3583 | Biotin-HPDP |
| Biotin-HPDP is a sulfhydryl-reactive biotinylation agent. | |
| BCC3586 | Perindopril Erbumine |
| Angiotensin-converting enzyme (ACE) inhibitor (IC50 = 1.05 nM). Brain penetrant. Suppresses the increase in hippocampal ACE activity and improves cognition in PS2APP-transgenic mice. | |
| BCC3597 | Romidepsin (FK228, depsipeptide) |
| Potent and selective inhibitor of class I histone deacetylases (HDACs) (IC50 values are 36, 47, 510 and 14,000 nM for HDAC1, HDAC2, HDAC4 and HDAC6 respectively). Exhibits cytotoxicity against various human tumor cell lines; also exhibits antitumor activity against human tumor xenografts. | |
| BCC3599 | Apicidin |
| Potent histone deacetylase (HDAC) inhibitor (IC50 = 0.7 nM in an enzyme activity assay). Antiangiogenic and anti-invasive; blocks proliferation of human stomach and breast cancer cells. Induces apoptosis and autophagy in human oral squamous carcinoma cells. | |
| BCC3603 | (-)-JQ1 |
| Inactive control for (+)-JQ1. Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains. | |
