Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC4930 | Primidone |
| Anticonvulsant. | |
| BCC4939 | Ropinirole HCl |
| Selective D2-like receptor agonist (D3 > D2 > D4). Causes biphasic spontaneous locomotor activity and contralateral circling in 6-OHDA-lesioned mice. Displays antiParkinsonian activity. | |
| BCC4949 | Calcifediol |
| Prohormone of calcitriol. Major circulating form of vitamin D. Suppresses PTH synthesis and secretion in bovine parathyroid cells (ED50 = 2 nM). | |
| BCC4950 | Calcitriol |
| Active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Displays calcemic actions; stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Exhibits antitumor activity; inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. | |
| BCC4955 | NXY-059 |
| Free radical trapping agent. Reduces infarct size and preserves brain function in several animal models of acute ischemic stroke. Neuroprotectant. | |
| BCC4962 | Alfacalcidol |
| Metabolite and prodrug of vitamin D3. Improves mechanical bone strength and bone mass; suppresses osteoclastic bone resorption in vivo. | |
| BCC4963 | Alprostadil |
| Prostaglandin with some selectivity for EP3 and EP4 receptors (Ki values are 1.1, 2.1, 36, 10 and 33 nM for mouse EP3, EP4, EP1, EP2 and IP receptors respectively). Inhibits platelet aggregation and is a vasodilator in vivo. | |
| BCC4970 | Nanchangmycin |
| Antiviral. Inhibits Zika virus entry in a range of cell types including primary placental fibroblast cells, HUVECs and UtMECs (IC50 values are 0.1, 0.4 and 0.97 μM in U2OS, HBMECs and Jeg-3 cells respectively). Also inhibits cellular uptake of West Nile, dengue, sindbis and chikungunya viruses. | |
