Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCC4901 | Diltiazem HCl |
| Antihypertensive and cardioprotective agent; an inhibitor of L-type Ca2+ channels. | |
| BCC4902 | Doxercalciferol |
| Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA). | |
| BCC4904 | Felbamate |
| Anticonvulsant, acting as an antagonist at the NMDA-associated glycine binding site. | |
| BCC4905 | Fluconazole |
| Triazole antifungal agent. Effective against Candida strains in vitro and in vivo. | |
| BCC4907 | Fluticasone propionate |
| High affinity, selective glucocorticoid receptor agonist (Kd = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC50 = 3.7 nM) in vitro. Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic anti-inflammatory agent with low oral bioavailability. Also potentiates KV1 channels (EC50 = 37 nM). | |
| BCC4913 | Idebenone |
| Antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitro and in vivo. Inhibits apoptosis of astrocytes via increased NGF production. | |
| BCC4914 | Itraconazole |
| SMO antagonist (IC50 = 690 nM); acts at different binding site to cyclopamine. Also cytochrome p450 inhibitor (IC50 = 16-26 nM). Inhibits cell cycle at G1 phase in vitro and blocks angiogenesis in vivo (IC50 = 160 nM). Antifungal. | |
| BCC4915 | L-Ascorbyl 6-palmitate |
| Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C, it is also used as an antioxidant food additive. | |
