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(Z)-Lachnophyllum lactone

CAS# 81122-95-4

(Z)-Lachnophyllum lactone

Catalog No. BCN4746----Order now to get a substantial discount!

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(Z)-Lachnophyllum lactone: 5mg $615 In Stock
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Quality Control of (Z)-Lachnophyllum lactone

Number of papers citing our products

Chemical structure

(Z)-Lachnophyllum lactone

3D structure

Chemical Properties of (Z)-Lachnophyllum lactone

Cas No. 81122-95-4 SDF Download SDF
PubChem ID 5380634 Appearance Oil
Formula C10H10O2 M.Wt 162.2
Type of Compound Lipids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (5Z)-5-hex-2-ynylidenefuran-2-one
SMILES CCCC#CC=C1C=CC(=O)O1
Standard InChIKey PHUPYFCPQIPDNQ-TWGQIWQCSA-N
Standard InChI InChI=1S/C10H10O2/c1-2-3-4-5-6-9-7-8-10(11)12-9/h6-8H,2-3H2,1H3/b9-6-
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (Z)-Lachnophyllum lactone

The herbs of Conyza stricta

Biological Activity of (Z)-Lachnophyllum lactone

Description4(Z)-Lachnophyllum lactone shows anti-fungi activity.
TargetsAntifection
In vitro

Bioassay-Directed Isolation and Identification of Phytotoxic and Fungitoxic Acetylenes from Conyza canadensis.[Reference: WebLink]

Journal of Agricultural and Food Chemistry, 2012, 60(23):5893-5898.

Conyza canadensis (L.) Cronquist syn. (horseweed) is a problematic and invasive weed with reported allelopathic properties.
METHODS AND RESULTS:
To identify the phytotoxic constituents of the aerial parts, a systematic bioactivity-guided fractionation of the dichloromethane extract was performed. Three active enyne derivatives, (2Z,8Z)-matricaria acid methyl ester, (4Z,8Z)-matricaria lactone, and 4(Z)-Lachnophyllum lactone, were identified. The lactones inhibited growth of the monocot Agrostis stolonifera (bentgrass) and the dicot Lactuca sativa (lettuce) at 1 mg mL(-1), while the (2Z,8Z)-matricaria acid methyl ester was less active. In a dose-response screening of the lactones for growth inhibitory activity against Lemna paucicostata ,4(Z)-Lachnophyllum lactone was the most active with an IC(50) of 104 μM, while the (4Z,8Z)-matricaria lactone was less active (IC(50) of 220 μM). In a fungal direct bioautography assay, the two lactones at 10 and 100 μg/spot inhibited growth of the plant pathogenic fungi Colletotrichum acutatum , Colletotrichum fragariae , and Colletotrichum gloeosporioides .
CONCLUSIONS:
In a dose-response screening of the lactones against six different plant pathogenic fungi, (4Z,8Z)-matricaria lactone was more active than the commercial fungicide azoxystrobin on Col. acutatum , Col. fragariae , and Col. gloeosporioides at 30 μM and about as active as the commercial fungicide captan against Col. gloeosporioides , while 4(Z)-Lachnophyllum lactone was less active.

(Z)-Lachnophyllum lactone Dilution Calculator

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(Z)-Lachnophyllum lactone Molarity Calculator

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Preparing Stock Solutions of (Z)-Lachnophyllum lactone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.1652 mL 30.8261 mL 61.6523 mL 123.3046 mL 154.1307 mL
5 mM 1.233 mL 6.1652 mL 12.3305 mL 24.6609 mL 30.8261 mL
10 mM 0.6165 mL 3.0826 mL 6.1652 mL 12.3305 mL 15.4131 mL
50 mM 0.1233 mL 0.6165 mL 1.233 mL 2.4661 mL 3.0826 mL
100 mM 0.0617 mL 0.3083 mL 0.6165 mL 1.233 mL 1.5413 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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