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5-Ethoxychelerthrine

CAS# 79559-55-0

5-Ethoxychelerthrine

2D Structure

Catalog No. BCC8105----Order now to get a substantial discount!

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Quality Control of 5-Ethoxychelerthrine

3D structure

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5-Ethoxychelerthrine

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Chemical Properties of 5-Ethoxychelerthrine

Cas No. 79559-55-0 SDF Download SDF
PubChem ID 124350807 Appearance Powder
Formula C23H23NO5 M.Wt 393.4
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-ethoxy-1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
SMILES CCOC1=CC2=C3C=CC(=C(C3=C[N+](=C2C4=CC5=C(C=C41)OCO5)C)OC)OC
Standard InChIKey UJVQDDLAYPRWNM-UHFFFAOYSA-N
Standard InChI InChI=1S/C23H22NO5/c1-5-27-19-9-15-13-6-7-18(25-3)23(26-4)17(13)11-24(2)22(15)16-10-21-20(8-14(16)19)28-12-29-21/h6-11H,5,12H2,1-4H3/q+1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 5-Ethoxychelerthrine

The herbs of Chelidonium majus

Biological Activity of 5-Ethoxychelerthrine

Description6-Ethoxychelerythrine has anti-bacterical activity, it exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
TargetsAntifection
In vitro

Chemical constituents, antimicrobial and antimalarial activities of Zanthoxylum monophyllum.[Pubmed: 21341176]

Planta Med. 2011 Sep;77(13):1542-4.


METHODS AND RESULTS:
From the leaves and bark of Zanthoxylum monophyllum, a new lignan, 3-methoxy-3',4'-methylenedioxylignan-4,8,9,9'-tetraol (1), has been isolated along with 22 known compounds (2- 23), fifteen of them reported for the first time from Z. monophyllum. Their chemical structures were elucidated using detailed spectroscopic studies and chemical analysis. All compounds were evaluated for antimicrobial and antiprotozoal activities.
CONCLUSIONS:
Alkaloids BIS-[6-(5,6-dihydro-chelerythrinyl)] ether (2) and 6-Ethoxychelerythrine (4) exhibited strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). Compound 4-methoxy-N-methyl-2-quinolone (9) exhibited significant activity against MRSA (IC50 value of 8.0 µM) while compound 5,8,4'-trihydroxy-3,7,3'-trimethoxyflavone (10) showed weak activity against Plasmodium falciparum.

5-Ethoxychelerthrine Dilution Calculator

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5-Ethoxychelerthrine Molarity Calculator

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Preparing Stock Solutions of 5-Ethoxychelerthrine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5419 mL 12.7097 mL 25.4194 mL 50.8388 mL 63.5486 mL
5 mM 0.5084 mL 2.5419 mL 5.0839 mL 10.1678 mL 12.7097 mL
10 mM 0.2542 mL 1.271 mL 2.5419 mL 5.0839 mL 6.3549 mL
50 mM 0.0508 mL 0.2542 mL 0.5084 mL 1.0168 mL 1.271 mL
100 mM 0.0254 mL 0.1271 mL 0.2542 mL 0.5084 mL 0.6355 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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