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6-Feruloylcatalpol

CAS# 770721-33-0

6-Feruloylcatalpol

2D Structure

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3D structure

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6-Feruloylcatalpol

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Chemical Properties of 6-Feruloylcatalpol

Cas No. 770721-33-0 SDF Download SDF
PubChem ID 146159403 Appearance Powder
Formula C25H30O13 M.Wt 538.5
Type of Compound Iridoids Storage Desiccate at -20°C
Synonyms 6-O-trans-Feruloylcatalpol
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2S)-2-(hydroxymethyl)-10-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-5-yl] 3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
SMILES COC1=C(C=CC(=C1)C=CC(=O)OC2C3C=COC(C3C4(C2O4)CO)OC5C(C(C(C(O5)CO)O)O)O)O
Standard InChIKey RMSKZOXJAHOIER-VOACHAMZSA-N
Standard InChI InChI=1S/C25H30O13/c1-33-14-8-11(2-4-13(14)28)3-5-16(29)36-21-12-6-7-34-23(17(12)25(10-27)22(21)38-25)37-24-20(32)19(31)18(30)15(9-26)35-24/h2-8,12,15,17-24,26-28,30-32H,9-10H2,1H3/t12?,15?,17?,18?,19?,20?,21?,22?,23?,24?,25-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

6-Feruloylcatalpol Dilution Calculator

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6-Feruloylcatalpol Molarity Calculator

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Preparing Stock Solutions of 6-Feruloylcatalpol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.857 mL 9.2851 mL 18.5701 mL 37.1402 mL 46.4253 mL
5 mM 0.3714 mL 1.857 mL 3.714 mL 7.428 mL 9.2851 mL
10 mM 0.1857 mL 0.9285 mL 1.857 mL 3.714 mL 4.6425 mL
50 mM 0.0371 mL 0.1857 mL 0.3714 mL 0.7428 mL 0.9285 mL
100 mM 0.0186 mL 0.0929 mL 0.1857 mL 0.3714 mL 0.4643 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 6-Feruloylcatalpol

Collagen synthesis-promoting and collagenase inhibitory activities of constituents isolated from the rhizomes of Picrorhiza kurroa Royle ex Benth.[Pubmed:32247053]

Fitoterapia. 2020 Jun;143:104584.

Three new acylated phenylethanoid glycosides, kurroaosides A (14), B (15), and C (16), and a new acylated cucurbitane-type triterpene glycoside, kurroaoside D (17), were isolated from a methanol extract of the rhizomes of Picrorhiza kurroa Royle ex Benth. (Plantaginaceae) along with 29 known isolates including 10 acylated phenylethanoid glycosides (18-27), three cucurbitane-type triterpene glycosides (32-34), and a nortriterpene glycoside (35). The structures of these new compounds (14-17), including their stereochemistry, were determined based on chemical and physicochemical evidence derived from NMR and MS analysis. Among the isolates, acylated iridoid glycosides, picrosides I (8), II (9), III (10), and IV (11) and 6-Feruloylcatalpol (12), phenylethanoid glycosides (14-16), triterpene glycosides, cucurbitacin B 2-O-beta-D-glucopyranoside (32) and 25-acetoxy-2-beta-D-glucopyranosyloxy-3,16,20-trihydroxy-9-methyl-19-norlanosta-5 -en-22-one (35), and an acetophenone glycoside, picein (36), significantly promoted collagen synthesis at 10-30 muM, with no cytotoxicity being observed at the effective concentrations. Furthermore, acylated phenylethanoid glycosides, calceolarioside A (19, IC50 = 69.2 muM), plantamajoside (20, 51.8 muM), isoplantamajoside (21, 76.8 muM), and scroside E (23, 65.5 muM), exhibited collagenase inhibitory activity equivalent to that of positive agents caffeic acid (75.6 muM) and epigallocatechin 3-O-gallate (75.4 muM).

Minor Iridoid and Phenol Glycosides of Picrorhiza kurrooa.[Pubmed:17262460]

Planta Med. 1989 Oct;55(5):467-9.

From the roots of PICRORHIZA KURROOA a new iridoid glycoside, 6-Feruloylcatalpol has been isolated, along with veronicoside and minecoside and two phenol glucosides, picein and androsin.

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