SpeciosideCAS# 72514-90-0 |
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| Cas No. | 72514-90-0 | SDF | Download SDF |
| PubChem ID | 6440489 | Appearance | Powder |
| Formula | C24H28O12 | M.Wt | 508.5 |
| Type of Compound | Iridoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(1aS,1bS,5aR,6S,6aS)-1a-(hydroxymethyl)-2-[(3R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,5a,6,6a-tetrahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-6-yl] (E)-3-(4-hydroxyphenyl)prop-2-enoate | ||
| SMILES | C1=COC(C2C1C(C3C2(O3)CO)OC(=O)C=CC4=CC=C(C=C4)O)OC5C(C(C(C(O5)CO)O)O)O | ||
| Standard InChIKey | SKNVKBJSSSJNCI-WEAAFWTASA-N | ||
| Standard InChI | InChI=1S/C24H28O12/c25-9-14-17(29)18(30)19(31)23(33-14)35-22-16-13(7-8-32-22)20(21-24(16,10-26)36-21)34-15(28)6-3-11-1-4-12(27)5-2-11/h1-8,13-14,16-23,25-27,29-31H,9-10H2/b6-3+/t13-,14-,16-,17-,18?,19-,20+,21+,22?,23?,24-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Callicarpa giraldiana
| Description | 1. Specioside has analgesic activity. 2. Specioside has anti-dyspeptic and astringent activities. 3. Specioside has liver stimulating and wound healing activities. 4. Specioside exhibits potent antioxidant activity. 5. Specioside ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans. |
| Targets | SOD |
Specioside Dilution Calculator
Specioside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9666 mL | 9.8328 mL | 19.6657 mL | 39.3314 mL | 49.1642 mL |
| 5 mM | 0.3933 mL | 1.9666 mL | 3.9331 mL | 7.8663 mL | 9.8328 mL |
| 10 mM | 0.1967 mL | 0.9833 mL | 1.9666 mL | 3.9331 mL | 4.9164 mL |
| 50 mM | 0.0393 mL | 0.1967 mL | 0.3933 mL | 0.7866 mL | 0.9833 mL |
| 100 mM | 0.0197 mL | 0.0983 mL | 0.1967 mL | 0.3933 mL | 0.4916 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Specioside ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans.[Pubmed:25619942]
Comp Biochem Physiol C Toxicol Pharmacol. 2015 Mar;169:25-34.
Specioside (6-O-coumaroylcatalpol) is an iridoid glucoside which possesses multifunctional activities viz. analgesic, antidyspeptic, astringent, liver stimulating and wound healing properties. The present study for the first time delineates stress alleviating and lifespan prolonging action of Specioside (SPC), isolated from Stereospermum suaveolens in the free living, multicellular nematode model Caenorhabditis elegans. A strong correlation between lifespan extension and stress modulation in adult worms was established in a dose dependent manner. The dietary intake of this phytomolecule elevated juglone induced oxidative and heat induced thermal stress tolerance in C. elegans. On evaluation, it was found that 25 muM dose of SPC significantly extended lifespan by 15.47% (P
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