8-Hydroxythymol

CAS# 4478-33-5

8-Hydroxythymol

2D Structure

Catalog No. BCN9348----Order now to get a substantial discount!

Product Name & Size Price Stock
8-Hydroxythymol: 5mg $374 In Stock
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Quality Control of 8-Hydroxythymol

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8-Hydroxythymol

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Chemical Properties of 8-Hydroxythymol

Cas No. 4478-33-5 SDF Download SDF
PubChem ID N/A Appearance Oil
Formula C10H14O2 M.Wt 166.2
Type of Compound Other Terpenoid Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

8-Hydroxythymol Dilution Calculator

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8-Hydroxythymol Molarity Calculator

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Preparing Stock Solutions of 8-Hydroxythymol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.0168 mL 30.0842 mL 60.1685 mL 120.3369 mL 150.4212 mL
5 mM 1.2034 mL 6.0168 mL 12.0337 mL 24.0674 mL 30.0842 mL
10 mM 0.6017 mL 3.0084 mL 6.0168 mL 12.0337 mL 15.0421 mL
50 mM 0.1203 mL 0.6017 mL 1.2034 mL 2.4067 mL 3.0084 mL
100 mM 0.0602 mL 0.3008 mL 0.6017 mL 1.2034 mL 1.5042 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 8-Hydroxythymol

New thymol derivatives and cytotoxic constituents from the root of Eupatorium cannabinum ssp. asiaticum.[Pubmed:25238078]

Chem Biodivers. 2014 Sep;11(9):1374-80.

Two new thymol (=5-methyl-2-(1-methylethyl)phenol) derivatives, 8,10-didehydro-9-(3-methylbutanoyl)thymol 3-O-tiglate (1) and 9-O-angeloyl-8-methoxythymol 3-O-isobutyrate (2), were isolated from the root of Eupatorium cannabinum ssp. asiaticum, together with six known compounds, 3-8. The structures of 1 and 2 were determined through extensive 1D/2D-NMR and MS analyses. Among the isolates, 9-acetoxy-8,10-epoxythymol 3-O-tiglate (3) was the most cytotoxic, with IC50 values of 0.02+/-0.01, 1.02+/-0.07, and 1.36+/-0.12 mug/ml, respectively, against DLD-1, CCRF-CEM, and HL-60 cell lines. In addition, 10-acetoxy-9-O-angeloyl-8-Hydroxythymol (4) and eupatobenzofuran (6) exhibited cytotoxicities, with IC50 values of 1.14+/-0.16 and 2.63+/-0.22, and 7.63+/-0.94 and 2.31+/-0.14 mug/ml, respectively, against DLD-1 and CCRF-CEM cell lines.

New 2,2-diphenylpropane and ethoxylated aromatic monoterpenes from Lavandula gibsoni (Lamiaceae).[Pubmed:23126635]

Nat Prod Res. 2013 Aug;27(15):1323-9.

A new substituted 2,2-diphenylpropane (1) and two new ethoxylated aromatic monoterpene alcohols (2 and 4) have been isolated from the acetone extract of the aerial parts of Lavandula gibsoni, along with the known compounds 8-hydroxycarvacrol (3), 8-Hydroxythymol (5), coumarin (6), 4-methylresorcinol (7), 7,4'-dimethylapigenin (8), salvigenin (9), beta-sitosteryl-3-O-beta-D-glucopyranosyl-6'-O-palmitate (10) and euscaphic acid D (11). The structures of the isolated compounds were assigned on the basis of their (1)H- and (13)C-NMR spectra and two-dimensional NMR techniques, which included COSY, HSQC, HMBC and NOESY experiments and comparison with the reported literature.

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