AAL Toxin TB2CAS# 149849-91-2 |
Quality Control & MSDS
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| Cas No. | 149849-91-2 | SDF | Download SDF |
| PubChem ID | 102004518 | Appearance | Powder |
| Formula | C25H47NO9 | M.Wt | 505.65 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-[2-[(3R,4R,5S,7S,14R,16S)-17-amino-5,14,16-trihydroxy-3,7-dimethylheptadecan-4-yl]oxy-2-oxoethyl]butanedioic acid | ||
| SMILES | CCC(C)C(C(CC(C)CCCCCCC(CC(CN)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O | ||
| Standard InChIKey | RXORSUNDLFDGCD-YVEDVMJTSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| Targets | Antifection |
AAL Toxin TB2 Dilution Calculator
AAL Toxin TB2 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9777 mL | 9.8883 mL | 19.7765 mL | 39.5531 mL | 49.4413 mL |
| 5 mM | 0.3955 mL | 1.9777 mL | 3.9553 mL | 7.9106 mL | 9.8883 mL |
| 10 mM | 0.1978 mL | 0.9888 mL | 1.9777 mL | 3.9553 mL | 4.9441 mL |
| 50 mM | 0.0396 mL | 0.1978 mL | 0.3955 mL | 0.7911 mL | 0.9888 mL |
| 100 mM | 0.0198 mL | 0.0989 mL | 0.1978 mL | 0.3955 mL | 0.4944 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Introduction of the AAL-toxin polyketide synthase gene ALT1 into FUM1-disrupted Fusarium verticillioides produces metabolites with the fumonisin methylation pattern.[Pubmed:19449880]
J Nat Prod. 2009 Jul;72(7):1328-30.
Fumonisins and AAL toxins(AAL Toxin TB1,AAL Toxin TB2,AAL Toxin TA2,AAL Toxin TA1,AAL Toxin TC1,AAL Toxin TC2, AAL Toxin TD1,AAL Toxin TD2,AAL Toxin TE1,AAL Toxin TE2) are polyketide-derived mycotoxins produced by several important fungal pathogens of crop plants. The toxins contain a linear, dimethylated polyketide chain, but differ in chain length and methylation positions. Here, we have isolated the major metabolites from a fumonisin null mutant, Fusarium verticillioides strain 5777, that has been transformed with the AAL Toxin TB2 polyketide synthase gene (ALT1). The results showed that the metabolites maintained the chain length and methylation pattern of fumonisins. This suggests that the timing and regioselectivity of the methyltransferase of the ALT1 PKS could be reprogrammed in this Fusarium transformant.
The presence and phytotoxicity of fumonisins and AAL-toxin in Alternaria alternata.[Pubmed:8835341]
Toxicon. 1996 Jan;34(1):133-6.
The fumonisins (FB) and AAL Toxin TB2 are known to be produced by Fusarium moniliforme and Alternaria alternata f. sp. lycopersici when grown on rice. Alternaria alternata produced 1.3-3.1 ppm FB1 when grown on PDA for 2 weeks at 26 degrees C as determined by CD-ELISA and 0.6 ppm as determined by CF/FAB/MS. ELISA consistently yielded higher results than CF/FAB/MS. The presence of FB2, FB3 and AAL-toxin were demonstrated in spores and mycelia of A. alternata by CF/FAB/MS. The presence of AAL Toxin TB2 was further confirmed by demonstration of increased free sphingoid bases in tomato plants exposed to fungal spores and mycelia. This is the first report of AAL Toxin TB2, FB2 and FB3 in spores and mycelia and confirms the presence of FB1 in A. alternata.
