Acetagastrodin

CAS# 64291-41-4

Acetagastrodin

Catalog No. BCN8155----Order now to get a substantial discount!

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Acetagastrodin: 5mg Please Inquire In Stock
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Quality Control of Acetagastrodin

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Chemical structure

Acetagastrodin

3D structure

Chemical Properties of Acetagastrodin

Cas No. 64291-41-4 SDF Download SDF
PubChem ID 163043 Appearance Powder
Formula C21H26O11 M.Wt 454.43
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-[4-(hydroxymethyl)phenoxy]oxan-2-yl]methyl acetate
SMILES CC(=O)OCC1C(C(C(C(O1)OC2=CC=C(C=C2)CO)OC(=O)C)OC(=O)C)OC(=O)C
Standard InChIKey HGUDVDQXCUHOED-YMQHIKHWSA-N
Standard InChI InChI=1S/C21H26O11/c1-11(23)27-10-17-18(28-12(2)24)19(29-13(3)25)20(30-14(4)26)21(32-17)31-16-7-5-15(9-22)6-8-16/h5-8,17-22H,9-10H2,1-4H3/t17-,18-,19+,20-,21-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Acetagastrodin

The herbs of Gastrodia elata

Biological Activity of Acetagastrodin

Description1. Acetagastrodin treatment may be an effective treatment to protect retinal neurons against such functional impairment during the early stages of diabetes. 2. Acetagastrodin has antispasmodic effect on vascular smooth muscle.

Acetagastrodin Dilution Calculator

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Acetagastrodin Molarity Calculator

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Preparing Stock Solutions of Acetagastrodin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2006 mL 11.0028 mL 22.0056 mL 44.0112 mL 55.014 mL
5 mM 0.4401 mL 2.2006 mL 4.4011 mL 8.8022 mL 11.0028 mL
10 mM 0.2201 mL 1.1003 mL 2.2006 mL 4.4011 mL 5.5014 mL
50 mM 0.044 mL 0.2201 mL 0.4401 mL 0.8802 mL 1.1003 mL
100 mM 0.022 mL 0.11 mL 0.2201 mL 0.4401 mL 0.5501 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Acetagastrodin

Acetagastrodin effects on retinal oscillatory potentials in patients during the early stages of diabetes.[Pubmed:27650536]

Acta Diabetol. 2017 Jan;54(1):73-79.

AIMS: To investigate the protective effect of Acetagastrodin on visual electrophysiology in patients with early-stage diabetes. METHODS: A prospective, randomized, controlled, double-blind trial was conducted. Subjects who were randomly assigned to either the treatment group or the control group were orally administered Acetagastrodin or placebo, respectively, for 6 months. The quantity, mean amplitude and mean latency of oscillatory potentials (OPs) wavelets at baseline and 6 months were measured on electroretinogram (ERG), in all subjects. RESULTS: A total of 92 right eyes in 92 patients with type 2 diabetes, who were diagnosed for the first time, were enrolled. Each group consisted of 46 cases (46 eyes). There was no significant difference in baseline characteristic between treatment and control groups at baseline, but quantity in treatment group was more than that in control group at 6 months (P = 0.001). The mean amplitude of OPs was reduced in the control group 6 months later compared with treatment group (P = 0.001). As to mean latency of OPs, statistical difference was also detectable between the treatment group and control group 6 months later (P < 0.001). No statistical differences were found in hemoglobin between both groups at 6 months (P > 0.05). CONCLUSIONS: Electrophysiological changes would go on worsening even hemoglobin was under control during the initial stage of diabetes. Acetagastrodin treatment may be an effective treatment to protect retinal neurons against such functional impairment during the early stages of diabetes.

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