L-QuebrachitolCAS# 642-38-6 |
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Quality Control & MSDS
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Chemical structure
3D structure
| Cas No. | 642-38-6 | SDF | Download SDF |
| PubChem ID | 151108 | Appearance | Powder |
| Formula | C7H14O6 | M.Wt | 194.18 |
| Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
| Solubility | DMSO : 250 mg/mL (1287.47 mM; Need ultrasonic) | ||
| Chemical Name | (1R,2S,4S,5R)-6-methoxycyclohexane-1,2,3,4,5-pentol | ||
| SMILES | COC1C(C(C(C(C1O)O)O)O)O | ||
| Standard InChIKey | DSCFFEYYQKSRSV-MBXCVVGISA-N | ||
| Standard InChI | InChI=1S/C7H14O6/c1-13-7-5(11)3(9)2(8)4(10)6(7)12/h2-12H,1H3/t2?,3-,4-,5+,6+,7?/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The barks of Aspidosperma desmanthum
| Description | 1. L-Quebrachitol can as a sugar substitute for diabetics. 2. Administration of sea buckthorn juice enriched in L-quebrachitol can increase fasting insulin level in plasma and show similar effects on random blood glucose level, glucose tolerance and the pancreatic tissue as observed for pure sea buckthorn juice. |
L-Quebrachitol Dilution Calculator
L-Quebrachitol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.1499 mL | 25.7493 mL | 51.4986 mL | 102.9972 mL | 128.7465 mL |
| 5 mM | 1.03 mL | 5.1499 mL | 10.2997 mL | 20.5994 mL | 25.7493 mL |
| 10 mM | 0.515 mL | 2.5749 mL | 5.1499 mL | 10.2997 mL | 12.8747 mL |
| 50 mM | 0.103 mL | 0.515 mL | 1.03 mL | 2.0599 mL | 2.5749 mL |
| 100 mM | 0.0515 mL | 0.2575 mL | 0.515 mL | 1.03 mL | 1.2875 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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First record of L-quebrachitol in Allophylus edulis (Sapindaceae).[Pubmed:18715552]
Carbohydr Res. 2008 Oct 13;343(15):2699-700.
Allophylus edulis, commonly called 'Chal chal', is a member of the Sapindaceae occurring in the Uruguayan and Brazilian native flora. During the phytochemical analysis of two Chal chal specimens from two well-differentiated geographical zones (Assis, Sao Paulo, Brazil, and Santa Lucia, Canelones, Uruguay), considerable amounts of L-Quebrachitol were isolated from both samples. The isolation was carried out from the ethanolic twig extracts obtained by maceration of both vegetal samples. White easily distinguishable crystals were mechanically separated, washed, and characterized by 1D and 2D NMR experiments and by MS data. Such techniques confirmed that the crystals isolated from sources collected in both countries resulted in the same compound, L-Quebrachitol, a natural product not previously reported for this species and one that has been investigated as a sugar substitute for diabetics. Worthy of note, the content of L-Quebrachitol in A. edulis may be the chemical basis to explain its ethnobotanical uses, since infusions of this plant are used to treat diabetes in the practice of local traditional medicine.
L-Quebrachitol is a natural product isolated from many plants, promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 (Runx2), MAPK (ERK, JNK, p38α), and Wnt/β-catenin signaling pathway.
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