AcrovestenolCAS# 864679-69-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 864679-69-6 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C32H42O9 | M.Wt | 570.7 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Acrovestenol Dilution Calculator
Acrovestenol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.7522 mL | 8.7612 mL | 17.5223 mL | 35.0447 mL | 43.8059 mL |
| 5 mM | 0.3504 mL | 1.7522 mL | 3.5045 mL | 7.0089 mL | 8.7612 mL |
| 10 mM | 0.1752 mL | 0.8761 mL | 1.7522 mL | 3.5045 mL | 4.3806 mL |
| 50 mM | 0.035 mL | 0.1752 mL | 0.3504 mL | 0.7009 mL | 0.8761 mL |
| 100 mM | 0.0175 mL | 0.0876 mL | 0.1752 mL | 0.3504 mL | 0.4381 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Acetophenones Isolated from Acronychia pedunculata and their Anti-proliferative Activities.[Pubmed:26996027]
Nat Prod Commun. 2016 Jan;11(1):83-6.
Study of the chemical constituents of Acronychia pedunculata (L.) Miq. (Rutaceae) stems collected in Taiwan led to the isolation and identification of eight known and three new acetophenones, named acrophenone A (1), B (2), and C (3). Of them, acrovestone (5), acropyrone (6) and Acrovestenol (7), which are dimer compounds, strikingly inhibited the proliferation of human leukemia cell lines.
Cytotoxic prenylated acetophenone dimers from Acronychia pedunculata.[Pubmed:22708987]
J Nat Prod. 2012 Jul 27;75(7):1270-6.
Three new acetophenone dimers or Acronychia-type acetophenones, acropyrone (1), acropyranol A (2), and acropyranol B (3), were isolated from the trunk bark of Acronychia pedunculata and structurally characterized, together with four known acetophenone dimers, acrovestone (4), Acrovestenol (5), acrofolione A (6), and acrofolione B (7), the acetophenone monomer acronyline (8), and four furoquinoline alkaloids. The chemical structures of the new isolated compounds were elucidated unambiguously by spectroscopic data analysis. The cytotoxic activities of the isolated acetophenone dimers were evaluated against the DU145 prostate and A2058 melanoma human cancer cell lines as well as the NHDF normal cell line. Acrovestone (4) and Acrovestenol (5) exhibited substantial cytotoxicity, with IC(50) values of 0.38 and 2.8 muM against A2058 melanoma cells as well as 0.93 and 2.7 muM against DU145 prostate cancer cells, respectively.
Aryl ketones from Acronychia pedunculata with cyclooxygenase-2 inhibitory effects.[Pubmed:17191994]
Chem Biodivers. 2005 Apr;2(4):463-9.
1-[2,4-Dihydroxy-6-methoxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl]ethanone (1), and a new aryl ketone, named Acrovestenol (2), were isolated as cyclooxygenase-2 (COX-2) inhibitory principles from a CH2Cl2 extract of the bark of Acronychia pedunculata by a bioassay-guided fractionation procedure. Compound 2 inhibited COX-2 with an IC50 value of 142.0+/-2.15 microM, compared to the COX-2 inhibitory reference compound NS-398 with an IC50 value of 11.3+/-1.12 microM. Compound 1 inhibited COX-2-catalyzed PG biosynthesis with 68% at a concentration of 500 microM. The structures were determined by UV, IR, and 1D- and 2D-NMR, including TOCSY, HSQC-DEPT, and HMBC, and MS investigations.
