Cimicifugoside H1CAS# 163046-73-9 |
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| Cas No. | 163046-73-9 | SDF | Download SDF |
| PubChem ID | 15241163 | Appearance | Powder |
| Formula | C35H52O9 | M.Wt | 616.78 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC(CC(=O)C1C(O1)(C)C)C2C(=O)CC3(C2(CC(C45C3=CCC6C4(C5)CCC(C6(C)C)OC7C(C(C(CO7)O)O)O)O)C)C | ||
| Standard InChIKey | PYBFXJMIKJNNAJ-GLWILYKISA-N | ||
| Standard InChI | InChI=1S/C35H52O9/c1-17(12-18(36)28-31(4,5)44-28)25-19(37)13-32(6)22-9-8-21-30(2,3)24(43-29-27(41)26(40)20(38)15-42-29)10-11-34(21)16-35(22,34)23(39)14-33(25,32)7/h9,17,20-21,23-29,38-41H,8,10-16H2,1-7H3/t17-,20-,21+,23+,24+,25+,26+,27-,28+,29+,32+,33-,34-,35+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Cimicifuga foetida
| Description | 1. Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia. |
Cimicifugoside H1 Dilution Calculator
Cimicifugoside H1 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.6213 mL | 8.1066 mL | 16.2132 mL | 32.4265 mL | 40.5331 mL |
| 5 mM | 0.3243 mL | 1.6213 mL | 3.2426 mL | 6.4853 mL | 8.1066 mL |
| 10 mM | 0.1621 mL | 0.8107 mL | 1.6213 mL | 3.2426 mL | 4.0533 mL |
| 50 mM | 0.0324 mL | 0.1621 mL | 0.3243 mL | 0.6485 mL | 0.8107 mL |
| 100 mM | 0.0162 mL | 0.0811 mL | 0.1621 mL | 0.3243 mL | 0.4053 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Cycloartane triterpenoid of Cimicifuga foetida].[Pubmed:19894537]
Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1930-4.
OBJECTIVE: To study cycloartane triterpenoid of Cimicifuga foetida and their osteoclast inhibition activity. METHOD: The compounds were isolated and purified by normal and reversed phase column chromatographic methods. Structures were identified by spectroscopic analyses. Their osteoclast inhibition activity was then studied. RESULT: Thirteen cycloartane triterpenoids were isolated from the rhizomes of C. foetida and were characterized as 25-O-acetyl-cimigenol (1), cimigenol (2), cimicidanol (3), 26-deoxyactein (4), asiaticoside A (5), 23-epi-26-deoxyactein (6), actein (7), 12beta-hydroxycimigenol (8), cimiside E (9), (23R, 24S) 25-O-acetyl-cimigenol-3-O-beta-D-xylopyranoside (10), (23R, 24S) cimigenol-3-O-beta-D-xylopyranoside (11), cimicifugoside H-1 (12) and cimicifugoside H-2 (13). CONCLUSION: Compound 5 was isolated from this genus for the first time, compound 7 was isolated firstly from the plant and compound 2, 7, 10 and 11 exhibit osteoclast inhibition activity.
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