Cleroindicin E

CAS# 165197-71-7

Cleroindicin E

2D Structure

Catalog No. BCN1729----Order now to get a substantial discount!

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Cleroindicin E: 5mg $748 In Stock
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Quality Control of Cleroindicin E

3D structure

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Cleroindicin E

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Chemical Properties of Cleroindicin E

Cas No. 165197-71-7 SDF Download SDF
PubChem ID 91895369 Appearance Oil
Formula C8H14O3 M.Wt 158.2
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3aS,6S,7aR)-3,4,5,6,7,7a-hexahydro-2H-1-benzofuran-3a,6-diol
SMILES C1CC2(CCOC2CC1O)O
Standard InChIKey BMCMOTVWVYIGFM-RNJXMRFFSA-N
Standard InChI InChI=1S/C8H14O3/c9-6-1-2-8(10)3-4-11-7(8)5-6/h6-7,9-10H,1-5H2/t6-,7+,8-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cleroindicin E

The herbs of Clerodendrum indicum

Protocol of Cleroindicin E

Structure Identification
Nat Prod Res. 2015 Jul 24:1-7.

Phytochemical analysis with the antioxidant and aldose reductase inhibitory capacities of Tephrosia humilis aerial parts' extracts.[Pubmed: 26209262]


METHODS AND RESULTS:
The phytochemical analysis showed the presence of 1,4-dihydroxy-3,4-(epoxyethano)-5-cyclohexene(1), Cleroindicin E(2), lupeol(3), methyl p-coumarate(4), methyl 4-hydroxybenzoate(5), prunin(6), 5,7,2',5'-tetrahydroxyflavanone 7-rutinoside(7), protocatechuic acid(8), luteolin 7-glucoside(9), apigenin(10), naringin(11), rhoifolin(12) and luteolin 7-glucuronate(13).

Cleroindicin E Dilution Calculator

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Cleroindicin E Molarity Calculator

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Preparing Stock Solutions of Cleroindicin E

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.3211 mL 31.6056 mL 63.2111 mL 126.4223 mL 158.0278 mL
5 mM 1.2642 mL 6.3211 mL 12.6422 mL 25.2845 mL 31.6056 mL
10 mM 0.6321 mL 3.1606 mL 6.3211 mL 12.6422 mL 15.8028 mL
50 mM 0.1264 mL 0.6321 mL 1.2642 mL 2.5284 mL 3.1606 mL
100 mM 0.0632 mL 0.3161 mL 0.6321 mL 1.2642 mL 1.5803 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cleroindicin E

Phytochemical analysis with the antioxidant and aldose reductase inhibitory capacities of Tephrosia humilis aerial parts' extracts.[Pubmed:26209262]

Nat Prod Res. 2016 Jun;30(12):1366-72.

The aerial parts of Tephrosia humilis were tested about their antioxidant potential, their ability to inhibit the aldose/aldehyde reductase enzymes and their phenolic content. The plant material was exhaustively extracted with petroleum ether, dichloromethane and methanol, consecutively. The concentrated methanol extract was re-extracted, successively, with diethyl ether, ethyl acetate and n-butanol. All extracts showed significant antioxidant capacity, but the most effective was the ethyl acetate extract. As about the aldose reductase inhibition, all fractions, except the aqueous, were strong inhibitors of the enzyme, with the n-butanolic and ethyl acetate fractions to inhibit the enzyme above 75%. These findings provide support to the ethnopharmacological usage of the plant as antioxidant and validate its potential to act against the long-term diabetic complications. The phytochemical analysis showed the presence of 1,4-dihydroxy-3,4-(epoxyethano)-5-cyclohexene(1), Cleroindicin E(2), lupeol(3), methyl p-coumarate(4), methyl 4-hydroxybenzoate(5), prunin(6), 5,7,2',5'-tetrahydroxyflavanone 7-rutinoside(7), protocatechuic acid(8), luteolin 7-glucoside(9), apigenin(10), naringin(11), rhoifolin(12) and luteolin 7-glucuronate(13).

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